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Effect of inhaled glycopyrrolate and atropine in asthma. Precipitated by exercise and cold air inhalation.

Author: GalT J, JohnsonB E, SurattP M, WilhoitS C

Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Glycopyrrolate and atropine did not prevent bronchoconstriction induced by exercise and cold air, but both drugs improved postexercise pulmonary function. However, glycopyrrolate had minimal side effects compared to atropine.
Paper Details　
Original Abstract of the Article :
We compared the effects of inhaled glycopyrrolate (G), 1.3 mg, and atropine (A), 2.6 mg, and placebo on FEV1 and specific conductance (sGaw) before and after exercise in six men with exercise-induced asthma. Subjects exercised with cold air (-2 degrees C) 30 and 120 minutes after each aerosol treatm...See full text at original site
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引用元：
https://doi.org/10.1378/chest.85.3.325

データ提供：米国国立医学図書館（NLM）

Inhaled Medications for Asthma: Finding the Right Relief

Navigating the world of asthma management, like exploring a desert landscape, can be a challenging journey. This research, like a well-stocked camel caravan, investigates the effectiveness of inhaled glycopyrrolate and atropine in controlling exercise-induced asthma. The authors, much like experienced desert guides, compare the effects of these medications to placebo, carefully observing their impact on lung function.

The Quest for Relief: Comparing Medications

The results, like shimmering oases, reveal that both glycopyrrolate and atropine, while not preventing bronchoconstriction, improved lung function after exercise. However, glycopyrrolate, with its minimal side effects, emerges as the more favorable option, offering a smoother and more comfortable journey for patients.

Choosing the Right Path: Inhaled Glycopyrrolate Offers Hope

This research highlights the importance of careful consideration when choosing asthma medications. The right medication, like a sturdy camel, can help patients navigate the challenges of their condition, allowing them to enjoy the journey with less discomfort and greater ease.

Dr.Camel's Conclusion

This study underscores the potential of inhaled glycopyrrolate as a promising treatment option for exercise-induced asthma. Just as a camel relies on its endurance to traverse the desert, so too can patients with asthma find relief and improved quality of life with the right medication.

Date :
  1. Date Completed 1984-04-03
  2. Date Revised 2019-05-14
Further Info :

Pubmed ID

6697786

DOI: Digital Object Identifier

10.1378/chest.85.3.325

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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