Paper Details

  1. Home
  2. Paper Details

Flunisolide: a review of its pharmacological properties and therapeutic efficacy in rhinitis.

Author: AveryG S, BrogdenR N, HeelR D, PakesG E, SpeightT M

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Flunisolide, an intranasal corticosteroid, relieved nasal symptoms in both perennial and seasonal allergic rhinitis, being most effective in patients with an allergic component. It was as effective as intranasal beclomethasone and more effective than intranasal sodium cromoglycate. Side effects were transient, including nasal stinging and throat irritation.
Paper Details　
Original Abstract of the Article :
Flunisolide, a derivative of fluocinolone acetonide, is advocated for intranasal inhalation for the treatment of perennial and seasonal allergic rhinitis. It is rapidly absorbed by all routes of administration, but it quickly undergoes extensive first-pass metabolism to a 6 beta-hydroxylated metabol...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.2165/00003495-198019060-00001

データ提供：米国国立医学図書館（NLM）

Flunisolide: A Refreshing Oasis for Rhinitis

Rhinitis, an inflammation of the nasal passages, can cause a range of uncomfortable symptoms, including sneezing, runny nose, and congestion. This study examines the use of flunisolide, a nasal corticosteroid, for the treatment of perennial and seasonal allergic rhinitis.

The study reviews the pharmacological properties of flunisolide and its effectiveness in treating rhinitis. The authors discuss the absorption and metabolism of flunisolide and its ability to relieve nasal symptoms, particularly in patients with an allergic component to their rhinitis.

Flunisolide: A Potential Oasis for Allergic Rhinitis

The study suggests that flunisolide is an effective treatment for both perennial and seasonal allergic rhinitis, providing relief from nasal symptoms. It highlights the potential for flunisolide to reduce the need for systemic antihistamines, especially during peak pollen periods. The authors also note that flunisolide has been shown to be as effective as other intranasal corticosteroids, such as beclomethasone, and potentially more effective than intranasal sodium cromoglycate.

Navigating the Desert of Allergies: Relief and Management

Allergic rhinitis can be a persistent challenge, but flunisolide offers a potential oasis of relief. This study provides insights into the effectiveness of flunisolide and encourages individuals with allergic rhinitis to consult with a healthcare professional to discuss treatment options and find the best solution for managing their symptoms.

Dr.Camel's Conclusion

Flunisolide, a refreshing oasis in the desert of rhinitis, offers a potential solution for managing allergic symptoms. This study underscores the effectiveness of flunisolide in providing relief from nasal symptoms and reducing the need for other medications. Like a camel seeking a respite from the desert heat, individuals with allergic rhinitis can find comfort and relief with flunisolide.

Date :
  1. Date Completed 1980-09-26
  2. Date Revised 2021-09-01
Further Info :

Pubmed ID

6771116

DOI: Digital Object Identifier

10.2165/00003495-198019060-00001

Related Literature

Article Analysis
・Side Effects of cromolyn ophthalmic
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.