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Comparison of nebulised sodium cromoglycate and oral theophylline in controlling symptoms of chronic asthma in pre-school children: a double blind study.

Author: NewthC J, NewthC V, TurnerJ A

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study compared the efficacy of nebulized sodium cromoglycate and oral theophylline in 26 children with chronic asthma. Sodium cromoglycate was at least as effective as theophylline in controlling asthmatic symptoms. Theophylline was associated with numerous adverse side effects, while sodium cromoglycate was not.
Paper Details　
Original Abstract of the Article :
The efficacy of nebulised sodium cromoglycate and an oral theophylline solution at currently recommended doses were compared in one to six-year-old children with chronic asthma. Twenty-six children completed a 24-week double-blind trial of treatment with sodium cromoglycate (SCG), theophylline and a...See full text at original site
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引用元：
https://doi.org/10.1111/j.1445-5994.1982.tb02467.x

データ提供：米国国立医学図書館（NLM）

Asthma in Preschoolers: A Quest for Relief

Asthma, a chronic respiratory condition, can significantly impact the lives of children. This study explores the effectiveness of two common treatments, nebulized sodium cromoglycate and oral theophylline, in controlling asthma symptoms in preschoolers.

A Double-Blind Trial in the Sand

Imagine two groups of children playing in the desert. One group receives a special elixir that's supposed to protect them from sandstorms, while the other group receives a placebo. This study is similar, with children randomly assigned to receive either nebulized sodium cromoglycate, oral theophylline, or a combination of both. The researchers carefully observed the children's asthma symptoms over a 24-week period.

Sodium Cromoglycate: A Protective Oasis

The study found that sodium cromoglycate, like a protective oasis in the desert, was at least as effective as theophylline in controlling asthma symptoms in preschoolers. This discovery is significant, as it offers a safe and effective treatment option for young children with asthma.

Dr.Camel's Conclusion

This study provides valuable insights into asthma management in preschoolers. The findings suggest that nebulized sodium cromoglycate offers a viable and effective treatment option for young children, providing a safe alternative to oral theophylline. This research underscores the importance of finding the right treatment for each individual patient, tailoring approaches to their specific needs and ensuring optimal outcomes.

Date :
  1. Date Completed 1982-10-21
  2. Date Revised 2019-08-25
Further Info :

Pubmed ID

6810863

DOI: Digital Object Identifier

10.1111/j.1445-5994.1982.tb02467.x

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PICO Info
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Languages

English

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