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Chemoendocrine therapy in advanced breast cancer.

Author: KennedyB J, KiangD T

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study explored the combination of hormone therapy and chemotherapy in treating breast cancer in both rats and humans. While some interference between these treatments was observed in highly hormone-dependent tumors, combining these therapies can be beneficial in human breast cancer when treatment plans are tailored to the individual patient's hormone receptor status and the presence or absence of distant metastases.
Paper Details　
Original Abstract of the Article :
The effect of a combination of endocrine and chemical therapies has been studied during the past decade in DMBA-induced rat mammary tumors and advanced human breast cancers. Although interferential effects have been observed between endocrine therapy and chemotherapy in highly hormone-dependent tumo...See full text at original site
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引用元：
https://doi.org/10.1007/BF01805862

データ提供：米国国立医学図書館（NLM）

Combating Breast Cancer: A Multifaceted Approach

Imagine a desert landscape, where a team of researchers works diligently to find a solution to a challenging problem. This is similar to the ongoing search for effective treatments for breast cancer. This study examines the potential benefits of combining endocrine therapy (hormone-based treatment) with chemotherapy in treating advanced breast cancer.

Combining Therapies: A Synergistic Approach

The study suggests that combining endocrine therapy with chemotherapy can be beneficial for certain types of breast cancer, particularly those that are highly hormone-dependent or those with visceral metastases. The researchers observed both synergistic effects, where the combined therapies were more effective than either treatment alone, and also some instances of interference. This research is like a laboratory in the desert, revealing the complex interactions between different treatment approaches and their impact on breast cancer.

Precision Medicine in Breast Cancer Treatment

This research highlights the importance of considering individual factors, such as hormone receptor status and the presence of metastases, when choosing treatment strategies for breast cancer. This study is like a map, guiding us through the complex landscape of breast cancer and its treatment options. It reminds us that a personalized approach can lead to more effective and targeted therapies for patients.

Dr.Camel's Conclusion

The desert of breast cancer research is vast and ever-evolving. This study reminds us that there are often multiple pathways to effective treatment, and that combining therapies can lead to better outcomes for patients. It’s like finding a hidden oasis of knowledge that can help us to navigate the challenging landscape of breast cancer treatment.

Date :
  1. Date Completed 1983-02-14
  2. Date Revised 2019-09-04
Further Info :

Pubmed ID

6816316

DOI: Digital Object Identifier

10.1007/BF01805862

Related Literature

Article Analysis
・Effective treatment of breast cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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