Paper Details 
Original Abstract of the Article :
Ninety-six depressed outpatients from 5 centres were given viloxazine 200-400 mg/day. The treatment produced significant clinical improvement as evaluated by the Hamilton Rating Scale for Depression. Thirteen patients dropped-out because of possible side effects. Many untoward symptoms were describe...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1007/BF00613832

データ提供:米国国立医学図書館(NLM)

Identifying Unwanted Symptoms in Depressed Patients Treated with Viloxazine

The field of depression treatment is always seeking better and safer medications to alleviate the suffering of patients. This study examines the experience of patients treated with viloxazine, an antidepressant, and explores the challenge of distinguishing between symptoms related to the underlying depression and potential side effects of the medication.

The researchers analyzed data from 96 depressed outpatients who received viloxazine at varying doses. While the medication showed significant improvement in depression scores, 13 patients discontinued treatment due to possible side effects. The researchers developed a unique algorithm to differentiate between illness-related symptoms (IRSs) and potential side effect symptoms (SESs), focusing on the time course of both the symptom and the illness. This algorithm helped identify 90 of the 187 reported symptoms as IRSs, leaving 97 potential SESs for further investigation.

The Importance of Careful Symptom Evaluation

This study highlights the complexity of symptom assessment in patients treated for depression, emphasizing the need for careful evaluation to distinguish between symptoms related to the illness and potential side effects of medication. While viloxazine was effective in treating depression, the study revealed a significant number of reported symptoms. Only a small number of these symptoms were considered potentially related to the medication.

Managing Symptoms and Promoting Patient Well-being

This research underscores the importance of open communication between patients and their doctors about any symptoms they experience during treatment for depression. By carefully monitoring symptoms, doctors can better identify potential side effects, adjust treatment plans accordingly, and ensure the well-being of their patients. Think of it like this: in a desert, a traveler might encounter a variety of discomforts, from the scorching sun to thirst. It's important to distinguish between these natural challenges of the environment and any potential health problems that might arise. Likewise, in treating depression, patients and doctors must work together to differentiate between symptoms of the illness and potential side effects of medication.

Dr. Camel's Conclusion

This study underscores the importance of careful symptom monitoring and accurate diagnosis in depression treatment. It highlights the need for open communication between patients and doctors, allowing for a better understanding of potential side effects and the development of personalized treatment plans.

Date :
  1. Date Completed 1983-06-10
  2. Date Revised 2019-08-13
Further Info :

Pubmed ID

6840180

DOI: Digital Object Identifier

10.1007/BF00613832

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.