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Adverse effects of brompheniramine on pulmonary function in a subset of asthmatic children.

Author: SchullerD E

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Antihistamines can be harmful to some asthmatic children, causing chest tightness and wheezing. Theophylline may prevent this adverse effect.
Paper Details　
Original Abstract of the Article :
The role of antihistamines in the therapy of bronchial asthma has remained controversial. Early studies suggested a possible aggravation of symptoms but more recent studies implied their safety. Ten asthmatic children who reported a feeling of chest tightness and subsequent wheezing after taking a p...See full text at original site
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引用元：
https://doi.org/10.1016/0091-6749(83)90526-2

データ提供：米国国立医学図書館（NLM）

Brompheniramine: A Cautionary Tale for Asthmatic Children

This study explores the potential adverse effects of brompheniramine, an antihistamine, on pulmonary function in a subset of asthmatic children. The research investigates the relationship between brompheniramine exposure and respiratory symptoms, particularly in children who experience chest tightness and wheezing after taking the medication. The authors perform a controlled challenge study to assess the impact of brompheniramine on pulmonary function, highlighting the potential risks associated with its use in certain asthmatic children. This study contributes to our understanding of the complex interplay between antihistamines and asthma, underscoring the importance of careful medication selection and individualized treatment approaches.

Brompheniramine: A Cautionary Note for Asthmatic Children

This study unveils the potential adverse effects of brompheniramine, an antihistamine, on pulmonary function in a subset of asthmatic children. The findings suggest that brompheniramine can trigger respiratory symptoms, particularly chest tightness and wheezing, in certain children. This research underscores the importance of considering individual patient characteristics and potential medication sensitivities when treating asthmatic children, ensuring the safe and effective management of their condition.

Brompheniramine: A Potential Pitfall in the Desert of Asthma Management

The desert of asthma management can be fraught with challenges, particularly in navigating the complex interplay between medications and individual patient responses. This study highlights a potential pitfall in the use of brompheniramine, an antihistamine, in certain asthmatic children. The findings emphasize the importance of careful medication selection and individualized treatment approaches, ensuring the safe and effective management of this chronic condition.

Dr.Camel's Conclusion

This study explores the potential adverse effects of brompheniramine, an antihistamine, on pulmonary function in a subset of asthmatic children. The findings suggest that brompheniramine can trigger respiratory symptoms, particularly chest tightness and wheezing, in certain children. This research underscores the importance of considering individual patient characteristics and potential medication sensitivities when treating asthmatic children, ensuring the safe and effective management of their condition.
Date :
  1. Date Completed 1983-10-08
  2. Date Revised 2019-07-23
Further Info :

Pubmed ID

6886255

DOI: Digital Object Identifier

10.1016/0091-6749(83)90526-2

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PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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