Paper Details

  1. Home
  2. Paper Details

A controlled trial of different treatment regimens in patients with urinary tract infections after lower urinary tract surgery.

Author: BarnoutiH, ClarkeT K, CrosbyA C, EvansC M, HolmesS, KulatilakeA E

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

In a study of 104 people with urinary tract infections (UTIs) after catheterization or surgery, co-trimoxazole and cephradine were effective in treating the infections. Two doses of co-trimoxazole or cephradine per day for a week successfully eradicated 93% and 88% of the UTIs, respectively. However, four doses of cephradine per day were only successful in 64% of patients. E. coli and coagulase-negative staphylococci were the most common bacteria causing the UTIs. The effectiveness of the antibiotics did not always correlate with their sensitivity in lab tests.
Paper Details　
Original Abstract of the Article :
One hundred and four patients who developed urinary tract infections after catheterization for acute retention of urine and surgery of the bladder or urethra were randomly allocated to four treatment groups. Analysis of the results in 65 patients showed that co-trimoxazole and 1 g cephradine adminis...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1185/03007998009109456

データ提供：米国国立医学図書館（NLM）

A Controlled Trial of Different Treatment Regimens in Patients with Urinary Tract Infections After Lower Urinary Tract Surgery

The world of medicine is a vast desert, and we’re constantly searching for the right treatment oasis for different ailments. In the realm of urinary tract infections (UTIs), researchers are working hard to find the best way to combat these pesky infections, especially after surgeries that involve the lower urinary tract. This study, like a well-equipped caravan venturing into the desert, sought to evaluate the effectiveness of various treatment regimens in patients who developed UTIs after undergoing bladder or urethral surgery. The researchers, armed with a randomized controlled trial design, divided 104 patients into four groups, each receiving a different antibiotic treatment. Their findings, like precious water in the desert, revealed that co-trimoxazole and cephradine administered twice daily for a week were highly effective in eradicating UTIs in 93% and 88% of the patients, respectively. However, the same dose of cephradine given four times a day was less successful, only eradicating 64% of the infections. In patients who received no treatment, the original infection persisted in 65% of cases.

The Importance of Choosing the Right Treatment

This research sheds light on the importance of selecting the right antibiotic and dosing regimen for UTIs. The findings suggest that co-trimoxazole and twice-daily cephradine are highly effective in treating UTIs, while the effectiveness of four-times-daily cephradine is significantly less. These results provide valuable information for healthcare providers to guide their treatment decisions in the desert of UTI management.

Finding Your UTI Oasis

It’s important to consult a healthcare professional for any UTI symptoms. They can determine the best treatment for you based on your individual needs. Like finding a well-hidden oasis in the desert, you can find relief with the right treatment and advice.

Dr.Camel's Conclusion

This study offers valuable insights into the treatment of UTIs, demonstrating that certain antibiotic regimens are more effective than others. It highlights the importance of carefully selecting the right treatment to ensure optimal outcomes for patients.

Date :
  1. Date Completed 1980-06-25
  2. Date Revised 2019-09-09
Further Info :

Pubmed ID

6988169

DOI: Digital Object Identifier

10.1185/03007998009109456

Related Literature

Article Analysis
・Effective treatment of urinary tract infections
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.