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Cimetidine treatment for the prevention of recurrence of duodenal ulcer: an international collaborative study.

Author: BeresfordJ, BurlandW L, HawkinsB W

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Cimetidine effectively reduces the recurrence of duodenal ulcers. It has few side effects and is well tolerated.
Paper Details　
Original Abstract of the Article :
Comparison of cimetidine and placebo in the prevention of recurrence of ulceration was carried out in the study of 696 patients with recently healed duodenal ulcers. Treatment with cimetidine 400 mg at bedtime or twice daily for up to 12 months very significantly reduced recurrence of symptomatic ul...See full text at original site
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引用元：
https://doi.org/10.1136/pgmj.56.653.173

データ提供：米国国立医学図書館（NLM）

Cimetidine: A Shield Against Ulcer Recurrence

The world of gastroenterology is a fascinating realm, where the delicate balance of stomach acid and mucosal protection plays a crucial role in our well-being. This research investigates the efficacy of cimetidine, a histamine H2 receptor antagonist, in preventing the recurrence of duodenal ulcers. The authors conducted an international collaborative study involving 696 patients with recently healed duodenal ulcers. They compared the effects of cimetidine treatment to placebo, with patients receiving either cimetidine 400 mg at bedtime or twice daily for up to 12 months.

Cimetidine: A Promising Shield

The results of this study indicate that cimetidine treatment significantly reduced the recurrence of symptomatic duodenal ulcers, both in the short term and long term. The authors observed a marked reduction in both symptomatic and asymptomatic ulcer recurrence in patients receiving cimetidine compared to those receiving placebo. This demonstrates the effectiveness of cimetidine in preventing duodenal ulcer recurrence.

A Beacon of Hope: Cimetidine for Ulcer Prevention

The study offers a beacon of hope for individuals struggling with recurrent duodenal ulcers. The findings suggest that cimetidine can be a valuable tool in preventing ulcer recurrence and improving overall gastrointestinal health. The research emphasizes the importance of personalized treatment plans and long-term management strategies to prevent ulcer recurrence.

Dr. Camel's Conclusion

This international collaborative study provides compelling evidence for the efficacy of cimetidine in preventing duodenal ulcer recurrence. The authors have diligently investigated the effects of cimetidine and have demonstrated its ability to significantly reduce the risk of ulcer recurrence. Their findings offer a valuable roadmap for improving the management of duodenal ulcers and promoting gastrointestinal well-being.

Date :
  1. Date Completed 1980-09-23
  2. Date Revised 2019-05-01
Further Info :

Pubmed ID

6994084

DOI: Digital Object Identifier

10.1136/pgmj.56.653.173

Related Literature

Article Analysis
・Effects of cimetidine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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