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Timolol versus pilocarpine separately or combined with acetazolamide-effects on intraocular pressure.

Author: CalissendorffB, MarénN, OstbergA, WettrellK

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Timolol and pilocarpine were equally effective in lowering intraocular pressure in patients with ocular hypertension or glaucoma. Acetazolamide was also effective in lowering intraocular pressure. Timolol was effective in most patients when administered once a day.
Paper Details　
Original Abstract of the Article :
Fifty-eight patients with intraocular hypertension or primary open angle glaucoma participated in a double masked randomized study. Timolol in concentrations 0.25% and 0.5% was compared with 1, 2, or 4% pilocarpine Acetazolamide (250 mg x 3) was added if intraocular pressure (IOP) was uncontrolled w...See full text at original site
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引用元：
https://doi.org/10.1111/j.1755-3768.1980.tb08304.x

データ提供：米国国立医学図書館（NLM）

Timolol, Pilocarpine, and Acetazolamide: A Comparative Study

The field of [ophthalmology] is constantly seeking to [improve treatment options] for [intraocular pressure] disorders. This study investigates the efficacy of [timolol], [pilocarpine], and [acetazolamide] in [reducing intraocular pressure].

Similar Efficacy: Timolol, Pilocarpine, and Acetazolamide

The authors found [no significant difference] in [hypotensive effect] between [timolol] and [pilocarpine], regardless of the concentration used. The [additive effect] of [acetazolamide] was [similar] for both [timolol] and [pilocarpine].

Managing Intraocular Pressure: A Personalized Approach

This study underscores the importance of [tailoring treatment] to [individual needs] when [managing intraocular pressure]. While [timolol] and [pilocarpine] appear to have [similar efficacy], the [optimal treatment plan] will depend on [individual factors], such as [patient tolerance], [side effects], and [lifestyle considerations].

Dr. Camel's Conclusion

Like the shifting sands of a desert, intraocular pressure can be variable. This study reveals that timolol and pilocarpine are valuable tools in the ophthalmologist's arsenal, offering similar efficacy in managing intraocular pressure. As with a desert journey, finding the right approach for each individual is crucial for achieving optimal results.

Date :
  1. Date Completed 1981-05-13
  2. Date Revised 2019-08-21
Further Info :

Pubmed ID

7010886

DOI: Digital Object Identifier

10.1111/j.1755-3768.1980.tb08304.x

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Article Analysis
・Effects of timolol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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