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Nifedipine and propranolol: a beneficial drug interaction.

Author: DargieH J, HarrisL, KriklerD M, KriklerS, LynchP G

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study of 16 patients with chronic stable angina found that both nifedipine and propranolol were more effective than placebo in reducing angina frequency and nitroglycerin consumption. The combination of nifedipine and propranolol was even more effective than either drug alone.
Paper Details　
Original Abstract of the Article :
The antianginal effects of two active drugs, nifedipine and propranolol, alone in combination, were compared with those of placebo in a double-blind clinical trial that included 16 patients with chronic stable angina triggered by exertion. A low dose and a high dose of the active drugs were used (ni...See full text at original site
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引用元：
https://doi.org/10.1016/0002-9343(81)90238-2

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 1981-11-22
  2. Date Revised 2019-06-27
Further Info :

Pubmed ID

7025625

DOI: Digital Object Identifier

10.1016/0002-9343(81)90238-2

Related Literature

Article Analysis
・Effective treatment of angina
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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