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A combination of amoxicillin and clavulanic acid in the treatment of respiratory tract infections caused by amoxicillin-resistant haemophilus influenzae.

Author: BeeuwkesH, RutgersV H

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Amoxicillin/clavulanic acid was effective in treating 25 out of 33 patients with chronic or recurrent respiratory tract infections, mainly bronchitis. The most common bacteria isolated was Haemophilus influenzae, with 20 out of 22 strains resistant to amoxicillin but sensitive to the combination of amoxicillin and clavulanic acid. Nine patients experienced side effects, with two discontinuing treatment.
Paper Details　
Original Abstract of the Article :
This study was undertaken to evaluate the efficacy of a fixed combination of amoxicillin and clavulanic acid in 33 patients with chronic or recurrent respiratory tract infections (R.T.I.), mainly bronchitis. In two patients bronchopneumonia was diagnosed, and in one cystic fibrosis. The patients wer...See full text at original site
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引用元：
https://doi.org/10.1007/BF01640725

データ提供：米国国立医学図書館（NLM）

Tackling Amoxicillin-Resistant Respiratory Infections

This research delves into the realm of [infectious diseases], specifically targeting the challenge of [amoxicillin-resistant respiratory infections]. The study employed a [clinical trial] approach to investigate the efficacy of a fixed combination of [amoxicillin and clavulanic acid] in treating patients with [chronic or recurrent respiratory tract infections]. The researchers discovered that this combination demonstrated [good clinical success in 17 patients and a clear improvement in another eight], signifying its potential as a valuable therapeutic option.

A Promising Solution for Amoxicillin-Resistant Infections

The study's findings suggest that the combination of [amoxicillin and clavulanic acid] holds significant promise as a treatment for [amoxicillin-resistant respiratory infections]. In particular, [20 out of 22 Haemophilus influenzae strains isolated were resistant to amoxicillin alone, but sensitive to the combination], highlighting the drug's effectiveness against a significant contributor to these infections.

A New Weapon in the Arsenal Against Respiratory Infections

The results of this study shed light on the potential benefits of [amoxicillin/clavulanic acid] in addressing [amoxicillin-resistant respiratory infections]. While recognizing the [side-effects reported in nine patients, with two discontinuing treatment], the research underscores the importance of this drug combination as a [useful therapeutic addition to the existing forms of treatment].

Dr.Camel's Conclusion

Just like a camel navigates the vast desert, this research provides a refreshing oasis of hope for those struggling with [amoxicillin-resistant respiratory infections]. The findings suggest that [amoxicillin/clavulanic acid] can be a valuable tool in combatting these infections, reminding us that with a bit of ingenuity and determination, even the most challenging obstacles can be overcome.

Date :
  1. Date Completed 1982-01-20
  2. Date Revised 2019-08-30
Further Info :

Pubmed ID

7028635

DOI: Digital Object Identifier

10.1007/BF01640725

Related Literature

Article Analysis
・Side Effects of amoxicillin and clavulanic acid
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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