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Effects of meclofenamate and captopril on renal and other regional vascular beds after mild haemorrhage in conscious rabbits.

Author: BanksR A, BeilinL J, DavidsonL, SoltysJ

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Prostaglandins were found to modulate regional blood flow in conscious rabbits subjected to mild haemorrhage. The dependence on vasodilator prostaglandins increased in the renal and splenic vascular beds.
Paper Details　
Original Abstract of the Article :
1. The role of prostaglandins and angiotensin II in blood flow regulation was studied in conscious rabbits subjected to mild haemorrhage. 2. Haemorrhage caused a 13% fall in arterial pressure and a 21% fall in cardiac output, responses which were unchanged by sodium meclofenamate, an inhibitor of pr...See full text at original site
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引用元：
https://doi.org/10.1042/cs0620169

データ提供：米国国立医学図書館（NLM）

Effects of Meclofenamate and Captopril on Renal and Other Regional Vascular Beds After Mild Haemorrhage in Conscious Rabbits

In the world of [pharmacology] and [physiology], understanding how different drugs affect the [vascular system] is crucial for developing effective treatments for various medical conditions. This study investigated the effects of [meclofenamate] and [captopril] on different [vascular beds] in [conscious rabbits] after [mild haemorrhage].

Influence of Drugs on Vascular Beds

This study examined the influence of [meclofenamate] and [captopril] on [renal blood flow] and [blood pressure] in [rabbits]. The researchers discovered that [meclofenamate] caused [renal vasoconstriction], while [captopril] caused [renal vasodilation].

Understanding Drug Effects

This study highlights the importance of considering the potential effects of drugs on different parts of the body, especially the [vascular system]. The researchers found that the effects of these drugs could vary depending on the specific [vascular bed].

Dr.Camel's Conclusion

This research is a testament to the intricate nature of the desert of [pharmacology]. It reminds us that the effects of drugs can be complex and that understanding these effects is crucial for ensuring patient safety and efficacy.
Date :
  1. Date Completed 1982-03-22
  2. Date Revised 2019-08-21
Further Info :

Pubmed ID

7032806

DOI: Digital Object Identifier

10.1042/cs0620169

Related Literature

Article Analysis
・Effects of meclofenamate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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