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Use of fixed doses of beta blocking drugs in the treatment of hypertension. Randomised study of atenolol and penbutolol.

Author: ChadhaD R, HoutzagersJ J, LameijerL D, VoermansL A

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Both atenolol and penbutolol were effective in controlling moderate hypertension in 45 patients. Atenolol was associated with more frequent bradycardia, while penbutolol may be useful for patients who experience bradycardia with other beta-blockers.
Paper Details　
Original Abstract of the Article :
Atenolol 100 mg and penbutolol 40 mg given once a day were both effective in controlling moderate hypertension, as judged by a randomised controlled, double-blind trial in 45 patients treated for six weeks. Both drugs significantly reduced the resting supine and erect blood pressures. No serious adv...See full text at original site
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引用元：
https://doi.org/10.1007/BF00637507

データ提供：米国国立医学図書館（NLM）

A Tale of Two Beta Blockers: Atenolol and Penbutolol in Hypertension Management

Hypertension, a common health concern, is often managed through medication, and this study investigates the effectiveness of two beta blockers, atenolol and penbutolol, in controlling moderate hypertension. The researchers conducted a randomized, double-blind trial comparing the effects of these two drugs on blood pressure. The study found that both atenolol and penbutolol effectively reduced blood pressure, demonstrating their potential as therapeutic agents for hypertension. The study also highlighted that penbutolol, with its intrinsic sympathomimetic activity, may be a suitable alternative for patients who experience bradycardia (slow heart rate) with other beta blockers.

Finding the Right Balance: Beta Blockers in Hypertension Management

This study provides valuable information regarding the effectiveness of atenolol and penbutolol in controlling moderate hypertension. The researchers' findings highlight the importance of personalized treatment approaches, taking into account individual factors such as bradycardia.

Managing Blood Pressure: A Holistic Approach to Hypertension

This study underscores the importance of a holistic approach to hypertension management, considering individual patient needs and exploring alternative treatments when necessary. The study highlights the potential benefits and limitations of beta blockers, emphasizing the need for careful monitoring and personalized care. As my dear friend, the camel, says, "Just as a camel adapts its pace to the desert landscape, we must adapt our treatment approaches to the unique needs of each individual, finding the right balance for optimal well-being."

Dr.Camel's Conclusion

This study demonstrates the effectiveness of both atenolol and penbutolol in controlling moderate hypertension. The research highlights the potential benefits of penbutolol for patients who experience bradycardia with other beta blockers.

Date :
  1. Date Completed 1982-07-08
  2. Date Revised 2019-08-13
Further Info :

Pubmed ID

7042370

DOI: Digital Object Identifier

10.1007/BF00637507

SNS
PICO Info
in preparation
Languages

English

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