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The treatment of mycosis fungoides with ointment-based mechlorethamine.
Author: DeneauD G, HoppeR T, PriceN M
Original Abstract of the Article :
The use of topical mechlorethamine hydrochloride in the treatment of skin disease has been restricted because of the frequent development of contact dermatitis. A series of 24 patients with mycosis fungoides in stages 1A (eight patients), 1B (15 patients), and 2 (one patient) were treated with ointm...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/7065680
データ提供:米国国立医学図書館(NLM)
Treating Mycosis Fungoides with Ointment-Based Mechlorethamine
Mycosis fungoides, a rare type of skin cancer, can be like a stubborn sandstorm, difficult to control. This study explored the use of ointment-based mechlorethamine, a chemotherapy drug, to treat the disease. The authors were concerned about the potential side effects of contact dermatitis, similar to the scorching sun causing irritation to the skin. However, they found that this new ointment formulation was effective in clearing the disease in many patients, with minimal side effects.
The Effectiveness of Ointment-Based Mechlorethamine
Out of 24 patients with mycosis fungoides, 15 of 18 patients with active disease saw complete clearing of their condition over a period of up to 27 months. This is like a desert oasis, providing relief and healing. Only two patients experienced a partial relapse during their evaluation periods. Furthermore, the incidence of contact dermatitis was very low, only 8% in individuals with a history of hypersensitivity to mechlorethamine and 0% in patients being exposed to the medication for the first time. This is like discovering a new type of camel that is resistant to harsh desert conditions.
A Promising Treatment for Mycosis Fungoides
This new ointment-based mechlorethamine preparation appears to be a promising treatment for mycosis fungoides, offering hope for patients seeking relief from this challenging condition. It's like finding a cool breeze in the middle of a sandstorm.
Dr.Camel's Conclusion
This study highlights the importance of innovation in cancer treatment. By finding ways to minimize side effects, researchers can develop more effective and tolerable therapies for patients. This is a testament to the enduring spirit of research and the search for better solutions in the face of adversity.
Date :
- Date Completed 1982-05-27
- Date Revised 2015-11-19
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