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The effectivenss of danazol on subsequent fertility in minimal endometriosis.

Author: BergerM J, SeibelM M, TaymorM L, WeinsteinF G

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study compared the effectiveness of danazol (a medication) versus no treatment for 65 women with minimal endometriosis. After surgery (laparoscopy, D&C, tubal lavage), 30% of the danazol-treated group conceived within 6 months, compared to 50% of the untreated group. This suggests that women with minimal endometriosis may be able to conceive naturally after surgery, especially older women for whom delaying treatment could significantly impact their fertility.
Paper Details　
Original Abstract of the Article :
Sixty-five patients with minimal endometriosis were studied for the purpose of prospectively comparing conservative medical management in the form of danazol with no therapy in the treatment of this disease. After completion of the basic infertility evaluation and correction of additional factors af...See full text at original site
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引用元：
https://doi.org/10.1016/s0015-0282(16)46630-6

データ提供：米国国立医学図書館（NLM）

Danazol and Minimal Endometriosis: A Balancing Act for Fertility

Endometriosis, a condition affecting reproductive health, often poses a challenge for fertility. This study investigates the impact of danazol, a medication commonly used to manage endometriosis, on subsequent fertility in patients with minimal endometriosis. The researchers conducted a prospective study involving 65 patients, comparing the effects of danazol treatment with no treatment after laparoscopy and other procedures aimed at enhancing fertility.

Danazol's Impact on Fertility: A Question of Timing

The study's findings reveal a nuanced picture of danazol's impact on fertility. While a higher percentage of untreated patients achieved conception compared to those treated with danazol, the study highlights the importance of considering the time frame for conception attempts. The study suggests that delaying conception attempts for 6 months might be a significant factor for older patients, emphasizing the need for individualized approaches to fertility management.

Navigating the Journey to Parenthood

This study underscores the importance of personalized fertility management. The findings highlight the need to carefully weigh the potential benefits and drawbacks of different treatment options, taking into account factors such as age and the desire for immediate conception. Like a camel navigating a challenging desert landscape, we must carefully evaluate the terrain ahead, considering individual factors and seeking the optimal path towards parenthood.

Dr. Camel's Conclusion

This study provides valuable insights into the impact of danazol on fertility in patients with minimal endometriosis. It underscores the need for individualized approaches, considering factors such as age and the desired time frame for conception. The quest for parenthood can be a complex journey, often requiring careful navigation through a maze of choices.

Date :
  1. Date Completed 1982-12-21
  2. Date Revised 2019-07-07
Further Info :

Pubmed ID

7128838

DOI: Digital Object Identifier

10.1016/s0015-0282(16)46630-6

Related Literature

Article Analysis
・Effective treatment of endometriosis
SNS
PICO Info
in preparation
Languages

English

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