Paper Details 
Original Abstract of the Article :
In an open multi-centre study, 51 patients with mild to moderate hypertension were treated with either a single dose of 40 mg penbutolol per day for 8 weeks or changed over at 4 weeks due to inadequate response with penbutolol alone to a single dose (1 tablet) of a fixed combination of 40 mg penbuto...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/7146039

データ提供:米国国立医学図書館(NLM)

Penbutolol and a Fixed Combination for Hypertension

Hypertension, a condition characterized by high blood pressure, affects a significant portion of the population. Imagine a team of researchers trekking through the desert of hypertension research, seeking effective treatments to combat this prevalent condition. This study aimed to evaluate the efficacy of penbutolol, a beta-blocker, and a fixed combination of penbutolol with furosemide, a diuretic, in treating hypertension. The authors conducted a multi-center study, where patients with mild to moderate hypertension received either penbutolol alone or the combination therapy. The study found that while penbutolol alone provided adequate blood pressure control for a majority of patients, the combination therapy proved effective in those who did not respond to penbutolol alone. This finding suggests that combining penbutolol with furosemide may be a valuable option for patients with hypertension who do not respond well to monotherapy.

A Combined Approach for Managing Hypertension

This study highlights the potential benefits of combining penbutolol with furosemide for managing hypertension in patients who do not respond adequately to monotherapy. The combination therapy showed greater blood pressure reduction and weight loss compared to penbutolol alone, suggesting a synergistic effect between the two medications. It's like discovering a new oasis in the desert of hypertension treatment, where the combination of different resources provides a more effective solution. This research encourages a personalized approach to managing hypertension, tailoring treatment strategies to the individual needs of each patient.

Navigating the Desert of High Blood Pressure

Hypertension is a common and serious health concern. This study offers valuable insights into the potential benefits of a fixed combination of penbutolol and furosemide in treating hypertension. It's a reminder that navigating the desert of high blood pressure requires finding effective strategies and adapting treatment approaches to individual needs. This research underscores the importance of careful monitoring and tailored treatment plans to ensure optimal management of hypertension.

Dr.Camel's Conclusion

This study provides evidence for the efficacy of a fixed combination of penbutolol and furosemide in treating hypertension. It highlights the importance of personalized medicine in hypertension management, suggesting that a combination approach may be necessary for some patients. It's a reminder that the desert of hypertension research is vast and requires continuous exploration to find the most effective solutions for managing this prevalent condition.

Date :
  1. Date Completed 1983-01-07
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

7146039

DOI: Digital Object Identifier

7146039

Related Literature

SNS
PICO Info
in preparation
Languages

English

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