Long-term treatment of duodenal ulcer with trimipramine. A double-blind study.

Author: DybS, EllekjaerE F, HalvorsenL, HovdenakN, LarsenS, MyrenJ, ValnesK, WetterhusS

Paper Details 
Original Abstract of the Article :
Sixty-two patients with healed duodenal or prepyloric ulcers completed a double-blind long-term trial with either 25 mg/day of trimipramine (32 patients) or placebo (30 patients). Endoscopy was performed when marked dyspeptic complaints occurred or after a 1-year follow-up study. Eleven patients in ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/7167734

データ提供:米国国立医学図書館(NLM)

Long-Term Treatment of Duodenal Ulcers with Trimipramine: A Double-Blind Study

Duodenal ulcers, like stubborn desert winds, can cause significant discomfort and pain. This study investigates the long-term effectiveness of trimipramine, an antidepressant, in preventing the recurrence of healed duodenal ulcers.

The researchers, like meticulous desert explorers, conducted a double-blind trial with 62 patients who had previously healed duodenal ulcers. They found that patients receiving trimipramine were significantly less likely to experience a relapse of their ulcers compared to those receiving a placebo. This finding suggests that trimipramine, despite being an antidepressant, may have a protective effect against duodenal ulcer recurrence.

A Novel Approach to Ulcer Prevention

This study, like a new oasis discovered in the desert, suggests a novel approach to preventing duodenal ulcer recurrence. The use of trimipramine, a drug traditionally associated with mental health, presents an intriguing and potentially effective option for managing this common gastrointestinal condition.

Understanding the Connections in Our Bodies

Our bodies are complex and interconnected, like a vast desert ecosystem. This study reminds us that seemingly unrelated conditions like depression and duodenal ulcers may share unexpected connections, highlighting the importance of holistic approaches to healthcare.

Dr.Camel's Conclusion

This research, like a hidden spring in the desert, offers a new perspective on treating duodenal ulcers. The use of trimipramine, like a desert oasis offering unexpected respite, demonstrates that the boundaries between different medical specialties can sometimes be blurred, leading to potential breakthroughs in treatment.

Date :
  1. Date Completed 1983-05-27
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

7167734

DOI: Digital Object Identifier

7167734

Related Literature

SNS
PICO Info
in preparation
Languages

English

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