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Manchester regional breast study--5 and 10 year results.

Author: LythgoeJ P, PalmerM K

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study of 1022 patients with early breast cancer found that postoperative radiotherapy significantly reduced the frequency of local recurrence in patients with clinical stage I cancer who underwent simple mastectomy. However, there was no difference in overall survival between those who received radiotherapy and those who did not. In patients with clinical stage II cancer, there was no significant difference in survival or local recurrence between simple mastectomy with radiotherapy and radical mastectomy.
Paper Details　
Original Abstract of the Article :
Patients with early breast cancer (n = 1022) were treated between March 1970 and October 1975 in a prospective clinical trial. The results are presented after follow-up of 5-10 years. Clinical stage I cancer cases (n = 714) were randomly allocated to treatment by simple mastectomy and postoperative ...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1002/bjs.1800691202

データ提供：米国国立医学図書館（NLM）

Early Breast Cancer Treatment: A Journey Through the Desert of Cancer Care

The journey through [breast cancer] treatment is often fraught with uncertainty and anxiety, much like navigating a vast and unforgiving desert. This study examines the long-term outcomes of different treatment approaches for early breast cancer. The researchers conducted a prospective clinical trial, comparing the effects of simple mastectomy with and without postoperative radiotherapy. The study found that early postoperative radiotherapy significantly reduced the frequency of local recurrence, highlighting its crucial role in managing early breast cancer. This research provides valuable insights into the long-term benefits of radiotherapy in breast cancer treatment.

Finding a Path to Optimal Breast Cancer Care

The study's findings underscore the importance of individualized treatment approaches for breast cancer, considering the specific characteristics of the disease and the patient's overall health. The research highlights the potential benefits of early postoperative radiotherapy in reducing the risk of local recurrence. This research provides a valuable resource for guiding treatment decisions for early breast cancer and ensuring optimal outcomes for patients.

Navigating the Terrain of Breast Cancer Treatment

This study underscores the importance of ongoing research and development to improve the management of breast cancer and enhance the quality of life for individuals living with this condition. The research highlights the importance of considering all treatment options and weighing the potential benefits and risks of each approach. It's like finding a hidden oasis in the desert of breast cancer treatment, offering a way to improve outcomes and provide hope for patients.

Dr.Camel's Conclusion

This research provides valuable insights into the long-term outcomes of different treatment approaches for early breast cancer. It highlights the potential benefits of early postoperative radiotherapy in reducing the risk of local recurrence. As with the vast and ever-changing desert landscape, the realm of breast cancer treatment requires ongoing exploration and innovation to find solutions that meet the diverse needs of patients.

Date :
  1. Date Completed 1983-02-14
  2. Date Revised 2019-07-05
Further Info :

Pubmed ID

7171967

DOI: Digital Object Identifier

10.1002/bjs.1800691202

Related Literature

Article Analysis
・Effective treatment of breast cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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