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Reducing side effects of carbonic anhydrase inhibitors.

Author: LichterP R

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study evaluated the side effects of carbonic anhydrase inhibitors (CAI) in 44 glaucoma patients. All patients were initially placed on acetazolamide, but 26 patients could not tolerate it. Of these, 22 were switched to methazolamide. While half experienced severe side effects from methazolamide, 88% had severe side effects from acetazolamide. Switching drugs, reducing dosage, gradual dosage increase, and patience may help manage CAI side effects.
Paper Details　
Original Abstract of the Article :
Carbonic anhydrase inhibitor (CAI) side effects are common, but not well understood. Many ideas have surfaced on how to reduce these side effects, even though there is little scientific evidence to support some of the advice. One recommendation involves switching drugs when patients are intolerant o...See full text at original site
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引用元：
https://doi.org/10.1016/s0161-6420(81)35040-4

データ提供：米国国立医学図書館（NLM）

Managing Side Effects of Carbonic Anhydrase Inhibitors: A Quest for Relief

Carbonic anhydrase inhibitors (CAIs) are a class of drugs commonly used to treat conditions such as glaucoma. However, they can also cause side effects, which can vary from person to person. This research explores strategies for managing side effects associated with CAIs, investigating the effectiveness of switching drugs, reducing dosage, and other approaches.

Finding Relief from CAI Side Effects

The study found that switching from acetazolamide to methazolamide could help manage side effects in some patients, but not all. The research suggests that other approaches, such as reducing dosage or gradually increasing dosage, may also be effective. This research provides valuable insights into the management of CAI side effects, highlighting the need for individualized treatment plans.

Understanding and Managing Side Effects

This research underscores the importance of understanding and managing side effects associated with CAI medications. The study highlights the need for individualized treatment plans, carefully considering the patient's specific needs and responses to medication. It is like a camel navigating the desert, adapting its route and pace to the challenges of the terrain.

Dr.Camel's Conclusion

This research explores strategies for managing side effects associated with carbonic anhydrase inhibitors (CAIs), investigating the effectiveness of switching drugs, reducing dosage, and other approaches. The study highlights the need for individualized treatment plans, carefully considering the patient's specific needs and responses to medication.

Date :
  1. Date Completed 1981-07-20
  2. Date Revised 2019-07-26
Further Info :

Pubmed ID

7231916

DOI: Digital Object Identifier

10.1016/s0161-6420(81)35040-4

Related Literature

Article Analysis
・Side Effects of methazolamide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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