Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. The Alendronate Phase III Osteoporosis Treatment Study Group.

Author: BellN H, BröllJ, DequekerJ, DownsR W, FavusM, LibermanU A, MinneH W, QuanH, Rodriguez-PortalesJ, WeissS R

Paper Details 
Original Abstract of the Article :
BACKGROUND: Postmenopausal osteoporosis is a serious health problem, and additional treatments are needed. METHODS: We studied the effects of oral alendronate, an aminobisphosphonate, on bone mineral density and the incidence of fractures and height loss in 994 women with postmenopausal osteoporosi...See full text at original site
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引用元:
https://doi.org/10.1056/NEJM199511303332201

データ提供:米国国立医学図書館(NLM)

Alendronate: A Fortress in the Desert of Osteoporosis

Osteoporosis, like a desert landscape eroded by wind and time, can weaken bones, making them susceptible to fractures. The field of bone health is constantly exploring ways to strengthen bones and prevent fractures, and this study, like a caravan seeking a safe haven, examines the effects of alendronate, an aminobisphosphonate, on bone mineral density and fracture incidence in postmenopausal women with osteoporosis.

The researchers conducted a large-scale clinical trial, comparing the effects of alendronate with placebo. They found that alendronate significantly increased bone mineral density at all skeletal sites, while placebo led to decreases. Furthermore, alendronate was associated with a significant reduction in the incidence of vertebral fractures.

A Fortress of Bone: The Power of Alendronate

This finding, like building a fortress against the harsh desert winds, demonstrates the effectiveness of alendronate in strengthening bones and reducing the risk of fractures.

Navigating the Desert of Osteoporosis

This research, like a beacon of hope in the desert of osteoporosis, underscores the importance of preventative measures to maintain bone health. It highlights the potential benefits of alendronate in reducing fracture risk and improving quality of life for postmenopausal women.

Dr. Camel's Conclusion

Alendronate, like a sturdy fortress built in the desert of osteoporosis, offers a powerful tool for strengthening bones and reducing fracture risk. This study reminds us that proactive measures can make a significant difference in maintaining bone health and navigating the challenges of osteoporosis.

Date :
  1. Date Completed 1995-12-01
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

7477143

DOI: Digital Object Identifier

10.1056/NEJM199511303332201

Related Literature

SNS
PICO Info
in preparation
Languages

English

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