[Results of resection and adjuvant therapy of liver metastases of primary colorectal tumors--a review of the literature].

Author: EnckeA, GogC, KochB, LorenzM, RossionI, Staib-SeblerE

Paper Details 
Original Abstract of the Article :
Natural history of patients with colorectal liver metastases is not significantly changed even by curative resection. The majority unfortunately relapse. The results of adjuvant treatment after resection were evaluated by analysis of 17 publications as well as by own data (60 patients). 340 patients...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/7502591

データ提供:米国国立医学図書館(NLM)

Resection and Adjuvant Therapy for Colorectal Liver Metastases: A Journey Through the Desert of Cancer

The desert of colorectal liver metastases (CLM) is a challenging landscape, with a high rate of relapse, even after seemingly successful surgical interventions. This review examines the role of adjuvant therapy after resection for CLM, navigating the complexities of different treatment approaches and their associated risks and benefits. It explores the use of various chemotherapy regimens, including intraarterial, systemic, intraportal, and intraperitoneal infusions, as well as immunotherapy approaches such as tumor vaccination and monoclonal antibodies.

Navigating the Sands of Relapse: Adjuvant Therapy for CLM

The authors meticulously analyze the results of 17 publications and their own data, revealing a complex picture of adjuvant treatment for CLM. While the review suggests that adjuvant therapy might offer some benefits, it acknowledges the lack of definitive evidence, emphasizing the need for ongoing studies to assess its true impact on survival and recurrence-free time. The authors also highlight the potential morbidity associated with various treatment approaches, underscoring the importance of careful patient selection and individualized treatment plans.

A Journey Through the Desert of Cancer: Finding Hope Amidst the Dunes

The journey through the desert of cancer is arduous and unpredictable. This review offers valuable insights into the complexities of adjuvant therapy for CLM, reminding us that the search for effective treatment strategies remains ongoing. We must continue to explore innovative approaches, refine existing therapies, and individualize treatment plans to provide the best possible care for those facing this challenging disease.

Dr. Camel's Conclusion

Navigating the desert of colorectal liver metastases is a complex and demanding endeavor. This review provides a comprehensive look at the role of adjuvant therapy after resection, highlighting the need for further research to establish its true impact on survival and recurrence. The journey through the desert of cancer requires ongoing exploration, with a focus on personalized strategies and innovative treatments that offer hope to those facing its challenges.

Date :
  1. Date Completed 1996-01-18
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

7502591

DOI: Digital Object Identifier

7502591

Related Literature

SNS
PICO Info
in preparation
Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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