Paper Details 
Original Abstract of the Article :
After a patient treated with lamotrigine (LTG) had suffered from thoracal pain and repolarisation deficiencies in the electrocardiogram (ECG), we prospectively investigated 20 patients with localization-related epilepsies to assess cardiovascular side effects of LTG. During the study, LTG was added ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/7533939

データ提供:米国国立医学図書館(NLM)

Cardiac Side Effects and ECG Changes with Lamotrigine?--A Clinical Study

This research delves into the complex world of [Pharmacology] and the potential cardiovascular effects of lamotrigine, a commonly prescribed antiepileptic drug. The study, like a camel caravan navigating a desert of pharmacological complexities, investigates the cardiovascular side effects of lamotrigine in patients with epilepsy. The researchers, like seasoned desert explorers, aimed to assess the drug's impact on heart rate, rhythm, and electrocardiogram (ECG) readings.

Lamotrigine's Cardiac Effects: A Desert of Uncertainties

The findings, like a desert landscape with both oases and arid stretches, reveal a reassuring picture. The study, like a well-traveled caravan route, suggests that lamotrigine, when added to stable dosages of other antiepileptic drugs, does not significantly increase the risk of clinically relevant cardiac side effects. The researchers observed only a few non-specific abnormalities on ECG traces, and these were transient and did not pose a significant health concern.

Navigating the Desert of Drug Safety

This research, like a compass guiding us through the desert of drug safety, highlights the importance of carefully monitoring patients for potential cardiovascular side effects. The findings suggest that lamotrigine, when used appropriately, appears to be a safe and effective treatment option for epilepsy, even in patients with pre-existing cardiac conditions. Further research is needed to fully understand the long-term cardiovascular effects of lamotrigine and to identify any potential risk factors.

Dr.Camel's Conclusion

This study, like a camel caravan traversing a desert of pharmacological complexities, explores the cardiac side effects of lamotrigine. The findings, like a well-preserved water source, suggest that lamotrigine appears to be a safe and effective antiepileptic drug. While further research is needed to fully understand the drug's long-term effects, this study provides reassurance for patients and healthcare providers alike.

Date :
  1. Date Completed 1995-04-12
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

7533939

DOI: Digital Object Identifier

7533939

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SNS
PICO Info
in preparation
Languages

German

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