Paper Details 
Original Abstract of the Article :
Seventeen male homosexual outpatients with limited but progressive AIDS-associated Kaposi's sarcoma (KS) of skin, lymph nodes, oral cavity, and gastrointestinum were consecutively enrolled in an open, nonrandomized, prospective study. Patients received low-dose IFN-alpha 2b (3 MIU t.i.w.) in combina...See full text at original site
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引用元:
https://doi.org/10.1097/00042560-199510020-00007

データ提供:米国国立医学図書館(NLM)

Interferon-Alpha 2b and Zidovudine: A Promising Combination for AIDS-Associated Kaposi's Sarcoma

The fight against [AIDS-associated Kaposi's sarcoma (KS)] is a challenging journey, akin to navigating a vast and unforgiving desert. This research explores the [efficacy and safety] of a combination therapy using [low-dose interferon-alpha 2b] and [zidovudine] in patients with [early-stage AIDS-associated KS]. The study evaluated the [therapeutic effectiveness] of this approach in a [prospective cohort] of patients.

A New Path in the Desert of AIDS-Related Cancers

The study found that [65%] of patients experienced [complete or partial remission] of KS, with some experiencing [lasting remission] for over [24 months]. The researchers noted a strong correlation between [treatment response] and [pretreatment CD4+ lymphocyte counts], suggesting the importance of [immune status] in [treatment outcome]. The combination therapy was generally well tolerated, with [minimal hematologic side effects].

Hope on the Horizon for Patients with AIDS-Associated KS

This research provides evidence for a [promising therapeutic option] for [early-stage AIDS-associated KS]. The [combination therapy] of [low-dose interferon-alpha 2b] and [zidovudine] offers a potential path to [remission] and [improved quality of life] for patients facing this challenging condition. Further research is needed to refine treatment protocols and explore the long-term benefits of this approach.

Dr.Camel's Conclusion

Like a camel seeking an oasis in a desert, patients with AIDS-associated KS often face a journey marked by hardship and uncertainty. This research offers a ray of hope by demonstrating the potential of a combination therapy to provide relief and improve outcomes. It's a testament to the ongoing efforts to combat this challenging disease and find new pathways to healing.

Date :
  1. Date Completed 1995-10-24
  2. Date Revised 2019-10-23
Further Info :

Pubmed ID

7552479

DOI: Digital Object Identifier

10.1097/00042560-199510020-00007

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Article Analysis
SNS
PICO Info
in preparation
Languages

English

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