Antifibrinolytic therapy in cardiac surgery.

Author: ChenR H, CooleyD A, FrazierO H

Paper Details 
Original Abstract of the Article :
Bleeding remains an important complication after repeat and complicated cardiac surgery. Although aprotinin has recently been approved by the Food and Drug Administration for use as an antifibrinolytic agent, many surgeons continue to have concerns about its added cost and potential side effects. We...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC325256/

データ提供:米国国立医学図書館(NLM)

Antifibrinolytic Therapy: A Balancing Act in Cardiac Surgery

Cardiac surgery, like navigating a treacherous desert, often presents risks and complications. Bleeding is a particular concern, especially in repeat and complicated surgeries. This study examines the use of antifibrinolytic therapy, a treatment that helps control bleeding, in cardiac surgery. Imagine a camel navigating a rocky terrain, using its sturdy hooves and keen instincts to avoid treacherous obstacles. This research explores how antifibrinolytic therapy can help surgeons navigate the delicate balance between stopping bleeding and promoting healing.

Epsilon-Aminocaproic Acid: A Potential Alternative to Aprotinin

The study suggests that a single intravenous dose of 10g of epsilon-aminocaproic acid, administered immediately before cardiopulmonary bypass, may be a safe, inexpensive, and effective alternative to aprotinin, another antifibrinolytic agent. This research explores a potentially more accessible and cost-effective approach to managing bleeding in cardiac surgery. It's like finding a hidden spring in the desert, offering a refreshing alternative to a more difficult and resource-intensive route.

Optimizing Safety and Effectiveness in Cardiac Surgery

This study emphasizes the ongoing search for better and more efficient ways to manage bleeding in cardiac surgery. Finding effective and cost-effective solutions is crucial for improving patient outcomes and minimizing risks. This research provides a valuable step forward in optimizing safety and effectiveness in cardiac surgery, paving the way for better patient care.

Dr.Camel's Conclusion

This research highlights the ongoing search for improved treatment options in cardiac surgery. Epsilon-aminocaproic acid shows promise as a safe and effective alternative to aprotinin, offering a potential solution for managing bleeding in complex procedures. Just as a camel navigates the desert with careful planning and resourcefulness, surgeons strive to find the best ways to care for their patients and minimize risks in a challenging environment.

Date :
  1. Date Completed 1995-12-28
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

7580358

DOI: Digital Object Identifier

PMC325256

Related Literature

SNS
PICO Info
in preparation
Languages

English

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