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Dissociations in the expression of the sedative effects of triazolam.

Author: HommerD, JoyceE, RawlingsR, SiroccoK, WeingartnerH J

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Triazolam, a hypnotic drug, impaired free recall in healthy volunteers in a dose-dependent manner, suggesting an effect on reflective processes.
Paper Details　
Original Abstract of the Article :
Fifteen normal volunteers were administered 0.250, 0.375, and 0.500 mg of triazolam and placebo in a double-blind repeated measures cross-over design. Subjects demonstrated dose-dependent impairments in free recall, a test of explicit memory requiring awareness and reflection, and sedation as assess...See full text at original site
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引用元：
https://doi.org/10.1007/BF02246050

データ提供：米国国立医学図書館（NLM）

Dissociations in the Expression of the Sedative Effects of Triazolam

This research investigates the sedative effects of triazolam, a benzodiazepine medication commonly used as a sleep aid. The study examined how triazolam affects different cognitive processes, specifically focusing on memory and sedation. The study aimed to determine whether the sedative effects of triazolam could account for its impact on memory performance.

Triazolam's Sedative Effects and Memory Impairment: A Complex Relationship

The results showed that triazolam impaired performance on a free recall memory test, which requires conscious retrieval of information. However, the study found that the sedative effects of triazolam, as measured by objective and subjective measures, did not fully account for the memory impairment. This suggests that triazolam may have additional effects on cognitive processes beyond sedation that contribute to memory deficits.

Navigating the World of Sleep Aids: Understanding the Effects of Triazolam

This research provides valuable insights into the complex effects of triazolam. While it can be effective for promoting sleep, it's important to be aware of its potential impact on memory and other cognitive functions. This research highlights the need for careful medication use and understanding the potential side effects. Just as a camel navigates the desert with a clear mind, we should prioritize cognitive health when choosing sleep aids.

Dr. Camel's Conclusion

This research suggests that triazolam's sedative effects may not fully explain its impact on memory. It highlights the need to consider the potential cognitive consequences of using benzodiazepines and to weigh these against their potential benefits. Understanding the nuanced effects of medications is crucial for making informed choices about our health and well-being.

Date :
  1. Date Completed 1995-10-19
  2. Date Revised 2019-07-26
Further Info :

Pubmed ID

7675946

DOI: Digital Object Identifier

10.1007/BF02246050

Related Literature

Article Analysis
・Effects of triazolam
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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