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Prevention of nonsteroidal anti-inflammatory drug-induced gastroduodenal ulcers: role of mucosal protective and gastric antisecretory drugs.

Author: AgrawalN M, DajaniE Z

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Misoprostol is more effective than other antiulcer drugs in preventing NSAID-induced gastric and duodenal ulcers in patients receiving chronic NSAID therapy.
Paper Details　
Original Abstract of the Article :
One of the most serious side effects of nonsteroidal anti-inflammatory drugs (NSAIDs) is upper gastrointestinal mucosal damage that may result in erosions, ulcerations and other serious complications. NSAIDs reduce endogenous prostaglandins, and this reduction is relevant to their pharmacology and t...See full text at original site
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引用元：
https://doi.org/10.1159/000171526

データ提供：米国国立医学図書館（NLM）

Protecting the Gut: Preventing Nonsteroidal Anti-inflammatory Drug-Induced Gastroduodenal Ulcers

This research explores the challenge of [Nonsteroidal Anti-inflammatory Drug (NSAID)-Induced Gastroduodenal Ulcers], a significant side effect of NSAID therapy. NSAIDs, commonly used to manage pain and inflammation, can unfortunately lead to ulcers in the stomach and duodenum, sometimes with serious consequences.

The researchers investigated the efficacy of various drugs, including mucosal protective agents, gastric antisecretory drugs, and misoprostol, in preventing NSAID-induced ulcers. Their findings reveal that misoprostol, a synthetic prostaglandin, stands out as the most effective drug for preventing NSAID-induced gastric and duodenal ulcers.

This review critically analyzes the evidence for different drug therapies, highlighting the superior efficacy of misoprostol in preventing NSAID-induced ulcers. It also emphasizes the importance of choosing appropriate preventive measures to minimize the risk of these adverse effects.

Misoprostol: A Shield for the Gut Against NSAID-Induced Ulcers

This research underscores the importance of protecting the gastrointestinal tract when using NSAIDs. Misoprostol emerges as a crucial tool for preventing NSAID-induced ulcers, offering a valuable strategy for minimizing the risk of these potentially serious side effects.

Protecting Your Gut: Choosing the Right Approach for NSAID Therapy

This research provides valuable insights into the management of NSAID-induced ulcers. It emphasizes the importance of selecting appropriate preventative measures, such as misoprostol, to minimize the risk of these adverse effects.

Dr. Camel's Conclusion

This review highlights the importance of preventing NSAID-induced ulcers by utilizing appropriate protective measures. Misoprostol, with its proven efficacy, stands out as a valuable tool for minimizing the risk of these potentially serious side effects.

Date :
  1. Date Completed 1995-05-01
  2. Date Revised 2018-02-15
Further Info :

Pubmed ID

7697902

DOI: Digital Object Identifier

10.1159/000171526

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