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Clinical evaluation of a new sulfonylurea in maturity onset diabetes - glipizide (K-4024).

Author: BandisodeM S, BoshellB R

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Glipizide, a new low dose sulfonylurea, was found to be effective in controlling hyperglycemia in diabetic patients, with low toxicity and few side effects.
Paper Details　
Original Abstract of the Article :
Glipizide, a new low dose sulfonylurea, was evaluated for its efficacy and toxicity in a double-blind controlled study. Forty adult-onset diabetics were treated with either chlorpropamide or glipizide. In ten out of twenty patients "excellent" to "good" control of hyperglycemia was achieved with gli...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/770300

データ提供：米国国立医学図書館（NLM）

Glipizide: A New Sulfonylurea for Maturity Onset Diabetes

Diabetology, a field that studies diabetes, constantly seeks new and effective therapies. This research evaluated the efficacy and toxicity of Glipizide, a new sulfonylurea, for the treatment of maturity-onset diabetes.

Glipizide: Effective in Controlling Hyperglycemia

The double-blind controlled study found that Glipizide was effective in controlling hyperglycemia in a significant proportion of patients. The study compared Glipizide to chlorpropamide, another sulfonylurea, and found that Glipizide was comparable in efficacy. Additionally, Glipizide was well-tolerated, with low toxicity and infrequent side effects.

Implications for Diabetes Management and Treatment Options

This research highlights the potential of Glipizide as a new and effective treatment option for maturity-onset diabetes. It's like discovering a new oasis in the desert of diabetes management. The findings suggest that Glipizide can be a valuable addition to the treatment arsenal for managing this condition.

Dr.Camel's Conclusion

This research suggests that Glipizide is a promising new treatment for maturity-onset diabetes. Like a cool breeze in a desert, it offers a new option for managing this challenging condition. However, it's important to remember that every individual is unique and treatment responses may vary.

Date :
  1. Date Completed 1976-07-06
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

770300

DOI: Digital Object Identifier

770300

Related Literature

Article Analysis
・Side Effects of glipizide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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