Anti-inflammatory effects of etodolac: comparison with other non-steroidal anti-inflammatory drugs.

Author: FujisawaH, InoueK, InoueY, KimuraK, KyoiT, MotonagaA, UedaF

Paper Details 
Original Abstract of the Article :
The anti-inflammatory effects of etodolac (Eto) were compared with those of 6 other anti-inflammatory drugs: indomethacin (Ind), diclofenac Na (Dic), piroxicam (Pir), naproxen (Nap), ketoprofen (Ket) and aspirin (Asp). Eto inhibited carrageenin-induced edema in rats, adjuvant-induced arthritis in ra...See full text at original site
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引用元:
https://doi.org/10.1248/bpb.17.1577

データ提供:米国国立医学図書館(NLM)

Etodolac: A Promising Anti-Inflammatory Agent

Navigating the vast desert of inflammatory diseases, researchers are constantly seeking effective and safe treatments. This study, like a caravan on a long journey, compared the anti-inflammatory effects of etodolac (Eto) with six other commonly used anti-inflammatory drugs, including indomethacin (Ind), diclofenac Na (Dic), piroxicam (Pir), naproxen (Nap), ketoprofen (Ket), and aspirin (Asp). The researchers evaluated the efficacy of these drugs in various animal models of inflammation.

Etodolac: A Powerful Anti-Inflammatory Agent

Etodolac demonstrated significant anti-inflammatory effects in all models tested, inhibiting carrageenin-induced edema in rats, adjuvant-induced arthritis in rats, acetic acid-induced writhing in mice, and brewer's yeast-induced hyperalgesia and fever in rats. The effectiveness of etodolac in reducing inflammation was comparable to or even surpassed that of some of the other drugs studied.

Etodolac: A Potential Option for Managing Inflammatory Diseases

This study highlights the promising potential of etodolac as a potent anti-inflammatory agent. While further research is needed to fully understand its long-term effects and optimal therapeutic use, this research offers a valuable contribution to the ongoing efforts to manage inflammatory diseases.

Dr.Camel's Conclusion

This study is like a wellspring of hope in the desert of inflammatory diseases, showcasing the impressive anti-inflammatory properties of etodolac. While more research is needed, this investigation offers promising prospects for developing effective and safe treatments for various inflammatory conditions.

Date :
  1. Date Completed 1995-06-08
  2. Date Revised 2019-07-19
Further Info :

Pubmed ID

7735198

DOI: Digital Object Identifier

10.1248/bpb.17.1577

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English

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