Paper Details

  1. Home
  2. Paper Details

[Pharmacokinetics and pharmacodynamics of calcium channel blockers].

Author: MayerO

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Calcium antagonists, such as verapamil, nifedipine, and dilthiazem, are effective in treating cardiovascular diseases. Newer generations of dihydropyridines, including felodipine, isradipine, and nitrendipine, show higher vascular selectivity at lower concentrations. The third generation, such as amlodipine and lacidipine, offers prolonged effects with fewer side effects.
Paper Details　
Original Abstract of the Article :
The author presents a review of the chemically heterogeneous group of calcium antagonists, focused on their pharmacodynamic properties. He includes in the older generation of calcium antagonists drugs like verapamil, dihydropyridines (nifedipine) and dilthiazem (Diacordin, Blocalcin). The newer gene...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/7762170

データ提供：米国国立医学図書館（NLM）

A Journey Through the Channels: Exploring the Pharmacokinetics and Pharmacodynamics of Calcium Channel Blockers

Calcium channel blockers are a class of drugs that are widely used to treat hypertension and other cardiovascular conditions. This study delves into the pharmacokinetics and pharmacodynamics of these drugs, exploring their effects on the body and their mechanisms of action. The author provides a comprehensive review of different generations of calcium channel blockers, including verapamil, dihydropyridines (nifedipine), diltiazem, felodipine, isradipine, nitrendipine, amlodipine, and lacidipine.

The study discusses the pharmacodynamic properties of these drugs, highlighting their selective actions on different types of calcium channels. It explores the advantages and disadvantages of different generations of calcium channel blockers, emphasizing the improved vascular selectivity and reduced side effects of newer generations. The study also discusses the importance of understanding the pharmacokinetics of these drugs, including their absorption, distribution, metabolism, and elimination, to optimize dosage and minimize adverse effects.

The Desert of Cardiovascular Disease: A Need for Effective Treatments

This study provides valuable insights into the mechanisms of action and pharmacokinetic properties of calcium channel blockers, contributing to our understanding of these important drugs.

A Journey Towards a Healthier Heart

This research highlights the importance of understanding the nuances of drug therapy, recognizing that different drugs may have different effects and side effects. It emphasizes the need for careful patient monitoring and personalized treatment approaches to optimize outcomes.

Dr.Camel's Conclusion

This review provides a detailed exploration of the pharmacokinetics and pharmacodynamics of calcium channel blockers, a class of drugs widely used for cardiovascular conditions. It highlights the importance of understanding the properties of these drugs to optimize treatment outcomes and minimize adverse effects.

Date :
  1. Date Completed 1995-06-27
  2. Date Revised 2006-11-15
Further Info :

Pubmed ID

7762170

DOI: Digital Object Identifier

7762170

Related Literature

Article Analysis
・Side Effects of isradipine
SNS
PICO Info
in preparation
Languages

Czech

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.