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Efficacy of drug treatment in obsessive-compulsive disorder. A meta-analytic review.

Author: BellantuonoC, PiccinelliM, PiniS, WilkinsonG

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Antidepressant drugs are effective in the short-term treatment of obsessive-compulsive disorder. Clomipramine and fluvoxamine had greater therapeutic efficacy than antidepressant drugs with no selective serotonergic properties.
Paper Details　
Original Abstract of the Article :
BACKGROUND: A review of the efficacy of antidepressant drug treatment in patients with obsessive-compulsive disorder (OCD), using a meta-analytic approach. METHOD: Randomised double-blind clinical trials of antidepressant drugs, carried out among patients with OCD and published in peer-reviewed jou...See full text at original site
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引用元：
https://doi.org/10.1192/bjp.166.4.424

データ提供：米国国立医学図書館（NLM）

The Efficacy of Antidepressant Drugs in Obsessive-Compulsive Disorder (OCD)

This research examines the efficacy of antidepressant drugs in treating patients with obsessive-compulsive disorder (OCD), drawing on a meta-analytic approach to analyze a large body of research. The authors focus on the effectiveness of clomipramine and selective serotonin re-uptake inhibitors (SSRIs), comparing their efficacy to placebo and other antidepressant medications. This study provides valuable insights into the role of antidepressant drugs in managing OCD.

Antidepressant Drugs: A Promising Treatment Option for OCD

The meta-analysis indicates that both clomipramine and SSRIs are effective in reducing obsessive-compulsive symptoms in the short-term. The study highlights the importance of considering these medications as treatment options for patients with OCD. This research helps to guide clinicians in making informed decisions about treatment strategies for this challenging disorder.

Understanding the Complexities of OCD

OCD is a complex and often debilitating disorder, and this research sheds light on the effectiveness of antidepressant medications in managing its symptoms. Understanding the efficacy of various treatment options is crucial for providing patients with appropriate care and support.

Dr. Camel's Conclusion

This research is like a caravan of knowledge, carrying valuable insights into the treatment of OCD. By analyzing the evidence from numerous studies, this research offers a comprehensive view of the efficacy of antidepressant drugs, highlighting the importance of considering these medications as part of a holistic treatment plan for patients with OCD.

Date :
  1. Date Completed 1995-07-31
  2. Date Revised 2019-07-05
Further Info :

Pubmed ID

7795913

DOI: Digital Object Identifier

10.1192/bjp.166.4.424

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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