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A dose-ranging study of the efficacy and safety of azelastine nasal spray in the treatment of seasonal allergic rhinitis with an acute model.

Author: BensonP M, FreitagJ, MeltzerE O, WeilerJ M, WeilerK, WidlitzM D

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Azelastine nasal spray was effective in treating seasonal allergic rhinitis, with onset of action within 2 to 3 hours.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Oral azelastine, a nonsteroidal antiinflammatory respiratory investigational drug has demonstrated activity in the treatment of allergic rhinitis and asthma with a good safety profile. METHODS: Azelastine nasal spray was compared with sustained-release oral chlorpheniramine maleate and ...See full text at original site
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引用元：
https://doi.org/10.1016/0091-6749(94)90115-5

データ提供：米国国立医学図書館（NLM）

Azelastine Nasal Spray: A Cool Breeze in the Desert of Allergies

This study explores the effectiveness and safety of azelastine nasal spray for treating seasonal allergic rhinitis, a condition that can make you feel like you’re stuck in a sandstorm of sneezing and congestion. The research investigates a dose-ranging approach to finding the optimal amount for relief.

Finding the Right Dose for Allergy Relief

The study found that azelastine nasal spray, when used in a twice-daily regimen, provided significant relief from allergic rhinitis symptoms. This is like finding a refreshing oasis in a desert of allergies, offering a clear path to relief.

Managing Allergy Symptoms

This study provides valuable information about the potential benefits of azelastine nasal spray for seasonal allergic rhinitis. It’s like having a handy camel caravan to transport you through the desert of allergy season, offering comfort and relief from the harsh elements.

Dr.Camel's Conclusion

This study highlights the importance of finding the right dose for medication to achieve maximum efficacy. It’s like a skilled camel driver navigating a desert, ensuring that the caravan is well-equipped for the journey. The research provides valuable insights into the treatment of seasonal allergies, offering hope for those seeking relief from these common symptoms.
Date :
  1. Date Completed 1995-01-25
  2. Date Revised 2019-07-23
Further Info :

Pubmed ID

7798545

DOI: Digital Object Identifier

10.1016/0091-6749(94)90115-5

Related Literature

Article Analysis
・Effects of azelastine nasal spray
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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