Paper Details 
Original Abstract of the Article :
The neuroprotective activity of riluzole has been studied on N-methyl-D-aspartate (NMDA)- or veratridine-induced toxicity in immature rat hippocampal slices. Neurodegeneration was assessed by the measurement of LDH release and histology. Veratridine-induced LDH release can be inhibited by 100 microM...See full text at original site
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引用元:
https://doi.org/10.1016/0304-3940(94)90053-1

データ提供:米国国立医学図書館(NLM)

Riluzole: A Potential Neuroprotective Agent

The search for effective treatments for neurodegenerative diseases is a challenging but crucial area of research. This study focuses on riluzole, a drug that shows promise for protecting neurons from damage. The authors investigated riluzole's neuroprotective activity against N-methyl-D-aspartate (NMDA)- or veratridine-induced toxicity in immature rat hippocampal slices. They found that riluzole effectively reduced neurodegeneration, as measured by LDH release and histological analysis, suggesting that riluzole could be a potential therapeutic agent for protecting neurons from damage. This research offers hope for those battling neurodegenerative diseases and underscores the potential of riluzole as a neuroprotective agent.

Hope in the Desert of Neurodegenerative Diseases

Riluzole's neuroprotective effects, as demonstrated in this study, are a beacon of hope for those struggling with neurodegenerative diseases. Its ability to reduce neurodegeneration in rat hippocampal slices offers promise for future research aimed at developing treatments that protect neurons from damage. This research is a testament to the ongoing efforts to combat neurodegenerative diseases, a journey through a vast and challenging desert.

Navigating the Desert of Neurological Protection

Riluzole's potential as a neuroprotective agent is an exciting development in the field of neuroscience. However, more research is needed to fully understand its efficacy and safety for treating neurodegenerative diseases. This research is a reminder that the desert of neurological protection is vast and complex, but with each discovery, we move closer to effective treatments.

Dr.Camel's Conclusion

This study demonstrates the neuroprotective effects of riluzole in rat hippocampal slices. While further research is needed, riluzole shows promise as a potential therapeutic agent for protecting neurons from damage. The journey through the desert of neurodegenerative diseases is arduous, but with each research discovery, we gain valuable insights into the intricate workings of the brain and potential avenues for treatment.

Date :
  1. Date Completed 1995-02-10
  2. Date Revised 2019-07-01
Further Info :

Pubmed ID

7824190

DOI: Digital Object Identifier

10.1016/0304-3940(94)90053-1

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Languages

English

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