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The International (Ludwig) Breast Cancer Study Group Trials I-IV: 15 years follow-up.

Author: Castiglione-GertschM, CollinsJ, Cortes-FunesH, ForbesJ, GelberR D, GoldhirschA, HackingA, JohnsenC, LindtnerJ, RudenstamC M

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Adjuvant systemic therapy improves disease-free and overall survival for breast cancer, with benefits from multi-agent chemotherapy, prolonged tamoxifen treatment, and ovarian ablation. Combining chemotherapy and endocrine therapy may provide additional benefits.
Paper Details　
Original Abstract of the Article :
Adjuvant systemic therapy prolongs disease-free and overall survival in both pre- and postmenopausal patients. Available data shown benefit from multi-agent chemotherapy, prolonged tamoxifen treatment, and ovarian ablation, and that the combination of chemo- and endocrine therapy might be advantageo...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/7826904

データ提供：米国国立医学図書館（NLM）

Breast Cancer: A Journey Through the Desert of Adjuvant Therapy

This research embarks on a comprehensive journey through the landscape of breast cancer treatment, specifically exploring the effectiveness of adjuvant systemic therapy. The researchers, like seasoned desert explorers navigating a challenging terrain, conducted a long-term follow-up study of patients with breast cancer, evaluating the impact of various treatment strategies on disease-free and overall survival. The study aimed to provide a clearer understanding of the most effective approaches for managing breast cancer, offering a roadmap for navigating this challenging disease.

A Shifting Sandscape of Adjuvant Therapies: Finding the Right Path

The researchers found that adjuvant systemic therapy, like a well-equipped caravan traversing a challenging desert, significantly improved both disease-free and overall survival in patients with breast cancer. The study highlights the benefits of multi-agent chemotherapy, prolonged tamoxifen treatment, and ovarian ablation, demonstrating the effectiveness of various treatment strategies in managing breast cancer. These findings provide a valuable resource for healthcare providers, offering guidance for tailoring treatment plans to the specific needs of each patient.

Navigating the Desert of Breast Cancer: A Compass of Hope

This study offers a comprehensive overview of the effectiveness of various adjuvant therapies for breast cancer, highlighting the importance of a multi-faceted approach to treatment. The research emphasizes the importance of ongoing research and innovation in this field, seeking to develop more effective and targeted therapies for breast cancer, offering a beacon of hope for patients facing this formidable foe.

Dr.Camel's Conclusion

This research provides valuable insight into the effectiveness of adjuvant systemic therapy for breast cancer, highlighting the importance of personalized treatment strategies and the ongoing quest for more effective therapies. The study underscores the vital role of research and innovation in the fight against breast cancer, offering a beacon of hope for patients and their families.

Date :
  1. Date Completed 1995-02-23
  2. Date Revised 2020-02-03
Further Info :

Pubmed ID

7826904

DOI: Digital Object Identifier

S0923-7534(19)63230-8

Related Literature

Article Analysis
・Effective treatment of breast cancer
SNS
PICO Info
in preparation
Languages

English

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