At equipotent doses, isradipine is better tolerated than amlodipine in patients with mild-to-moderate hypertension: a double-blind, randomized, parallel-group study.

Author: De KeyserP, DeblanderA, HermansL, LesaffreE, ScheysI, WestelinckK J

Paper Details 
Original Abstract of the Article :
1. The objective of this double-blind parallel-group study was to compare the tolerability of isradipine and amlodipine, specifically, the side-effects known to be related to the use of dihydropyridine calcium antagonists. 2. A total of 205 patients with mild-to-moderate essential hypertension were ...See full text at original site
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引用元:
https://doi.org/10.1111/j.1365-2125.1994.tb04363.x

データ提供:米国国立医学図書館(NLM)

Isradipine vs. Amlodipine: A Tolerability Showdown

Imagine two camels, both strong and healthy, embarking on a long journey across the desert. But one camel experiences side effects from a new type of hay, while the other remains unaffected. This study compares the tolerability of isradipine and amlodipine, two medications used to treat high blood pressure, focusing on the specific side effects associated with dihydropyridine calcium antagonists. The study aims to identify which medication is better tolerated in patients with mild-to-moderate hypertension.

Isradipine: A More Tolerable Option for Mild-to-Moderate Hypertension

The results of this study suggest that isradipine is better tolerated than amlodipine in patients with mild-to-moderate hypertension. While both medications effectively reduced blood pressure, isradipine was associated with fewer spontaneously reported adverse events compared to amlodipine. This suggests that isradipine might be a more suitable option for patients who are sensitive to the side effects of dihydropyridine calcium antagonists.

Navigating the Desert of Hypertension: Choosing the Right Medication

High blood pressure is a common health concern, like a sandstorm that can wreak havoc on your cardiovascular system. But with the right medications, like isradipine or amlodipine, you can control your blood pressure and protect your heart. It's important to discuss your options with your doctor and choose the medication that is best suited for your individual needs.

Dr.Camel's Conclusion

This study is a testament to the importance of personalized medicine. It highlights the need to consider individual tolerance levels when choosing medications. Like a wise camel choosing the best path through the desert, we must carefully select the medications that are right for us.

Date :
  1. Date Completed 1995-03-02
  2. Date Revised 2019-05-12
Further Info :

Pubmed ID

7833223

DOI: Digital Object Identifier

10.1111/j.1365-2125.1994.tb04363.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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