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A comparison of the acute behavioral effects of triazolam and temazepam in normal volunteers.

Author: BickelW K, HigginsS T, HughesJ R, RushC R

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.

Overview

Triazolam and temazepam both cause behavioral impairment and subjective effects, but temazepam may be more disruptive at higher doses, contradicting previous allegations that triazolam is more disruptive.
Paper Details　
Original Abstract of the Article :
Two experiments were conducted to assess the acute behavioral effects of triazolam and temazepam in healthy, non-drug abusing men in double-blind, placebo-controlled, crossover trials, where all subjects received all possible doses. These drugs were compared to examine allegations that triazolam pro...See full text at original site
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引用元：
https://doi.org/10.1007/BF02244887

データ提供：米国国立医学図書館（NLM）

Triazolam vs. Temazepam: A Comparative Study of Sedative Effects

Sedatives, like a gentle breeze in the desert, can provide relief from anxiety and insomnia. This study compares the acute behavioral effects of triazolam and temazepam, two commonly prescribed sedatives, in healthy volunteers.

Evaluating Behavioral Impairment: A Careful Assessment

The researchers conducted a double-blind, placebo-controlled, crossover study, carefully assessing the effects of various doses of triazolam and temazepam on memory, learning, psychomotor performance, and subjective ratings of drug effects. This is like meticulously comparing the effects of different desert herbs on a traveler's well-being.

Triazolam and Temazepam: Similar Effects, Different Profiles

The study found that both triazolam and temazepam can produce significant behavioral impairment, but at different doses. While triazolam produced greater impairment at lower doses, temazepam showed greater disruption at higher doses. This is akin to discovering that different desert plants, while providing similar benefits, have varying levels of potency and potential side effects.

Dr. Camel's Conclusion

This study provides valuable insights into the comparative effects of triazolam and temazepam. The findings suggest that both drugs can produce behavioral impairment, but at different doses and with varying levels of subjective effects. It is important to consult with a healthcare professional to determine the appropriate dose and type of sedative for your individual needs.
Date :
  1. Date Completed 1995-03-29
  2. Date Revised 2019-07-26
Further Info :

Pubmed ID

7871050

DOI: Digital Object Identifier

10.1007/BF02244887

Related Literature

Article Analysis
・Effects of triazolam
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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