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Ten-year results of a comparison of conservation with mastectomy in the treatment of stage I and II breast cancer.

Author: CowanK H, DanforthD N, GlatsteinE, JacobsonJ A, LichterA S, LippmanM E, OkunieffP, PierceL, SteinbergS M, d'AngeloT

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study compared lumpectomy with radiation to mastectomy for early-stage breast cancer in 1,843 women. The study, conducted between 1979 and 1987, is now updated with a median follow-up of over 10 years. The results of this long-term follow-up will be described in the rest of the paper.
Paper Details　
Original Abstract of the Article :
Breast-conservation therapy for early-stage breast cancer is now an accepted treatment, but there is still controversy about its comparability with mastectomy. Between 1979 and 1987, the National Cancer Institute conducted a randomized, single-institution trial comparing lumpectomy, axillary dissect...See full text at original site
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引用元：
https://doi.org/10.1056/NEJM199504063321402

データ提供：米国国立医学図書館（NLM）

Breast Cancer Treatment: Comparing Conservation and Mastectomy

Breast-conservation therapy, which involves removing the tumor and surrounding tissue while preserving the breast, is a common treatment for early-stage breast cancer. This study compares the long-term outcomes of breast-conservation therapy with mastectomy for stage I and II breast cancer. The researchers conducted a randomized trial, following patients for over a decade to assess survival rates and recurrence rates. Their findings provide valuable insights into the long-term effectiveness of both treatment approaches.

A Decade of Data: Comparing Breast Cancer Treatments

This study, with its extensive follow-up period, provides reassuring evidence that breast-conservation therapy can be as effective as mastectomy in treating early-stage breast cancer. The long-term survival rates and recurrence rates were similar for both treatment groups, highlighting the value of breast-conservation therapy for patients seeking to preserve their breast.

Breast Cancer: Navigating Treatment Options

This research provides valuable information for patients facing a breast cancer diagnosis. Consult with your oncologist to discuss the best treatment options for your individual needs, considering factors such as tumor size, stage, and personal preferences.

Dr. Camel's Conclusion

This research, like a desert journey where each step reveals new horizons, demonstrates the effectiveness of breast-conservation therapy in treating early-stage breast cancer. By providing patients with a range of treatment options, we empower them to make informed decisions that align with their values and preferences.

Date :
  1. Date Completed 1995-04-06
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

7877647

DOI: Digital Object Identifier

10.1056/NEJM199504063321402

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Article Analysis
・Effective treatment of breast cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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