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Nonsedating H1 antihistamines in chronic urticaria.

Author: MonroeE W

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Second-generation, nonsedating antihistamines, such as terfenadine, astemizole, loratadine, and cetirizine hydrochloride, are as effective as the potent first-generation antihistamines for treating chronic urticaria, but without the central nervous system and anticholinergic side effects. These agents are considered first-line treatment options.
Paper Details　
Original Abstract of the Article :
Histamine type 1 (H1) receptor antagonists are the principal therapy for chronic urticaria. Their usefulness, however, is sometimes compromised by undesirable central nervous system (CNS) side effects such as daytime sedation and anticholinergic side effects such as dry mouth. Second-generation, non...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/7903515

データ提供：米国国立医学図書館（NLM）

Second-Generation Antihistamines: A Game-Changer for Chronic Urticaria

Chronic urticaria, or hives, can be a real nuisance. This study explores the role of nonsedating H1 antihistamines in treating this condition. H1 receptor antagonists, or antihistamines, are the go-to treatment for chronic urticaria, but the first-generation antihistamines often come with undesirable side effects like daytime sedation and dry mouth. This research delves into the benefits of second-generation, nonsedating antihistamines, such as terfenadine, astemizole, loratadine, and cetirizine hydrochloride. The study shows that these newer antihistamines are just as effective as the older ones but without the bothersome side effects. While there have been reports of cardiovascular side effects with terfenadine and astemizole, these are rare and usually occur in cases of overdose or when taken with other medications that increase serum antihistamine levels. Another bonus? The second-generation antihistamines offer more convenient dosage schedules, compared to the more frequent dosing of the older agents.

A Smoother Ride for Chronic Urticaria

This study emphasizes the advantages of using second-generation antihistamines as first-line therapy for chronic urticaria. These newer medications can offer a more comfortable and effective treatment experience, potentially improving the quality of life for individuals suffering from chronic urticaria.

Finding Relief from Hives: Tips for Effective Treatment

The camel knows a thing or two about dealing with the unpredictable elements, and chronic urticaria can feel like a sandstorm of itchy bumps. This study offers a helpful guide for treating chronic urticaria. Remember to discuss your treatment options with your doctor, as the best approach can vary depending on your individual situation.

Dr.Camel's Conclusion

The camel appreciates a good, soothing oasis, and this study offers a refreshing oasis for individuals with chronic urticaria. The researchers highlight the importance of choosing the right antihistamine for the job, emphasizing the benefits of second-generation, nonsedating options for a more comfortable and effective treatment experience.

Date :
  1. Date Completed 1994-01-26
  2. Date Revised 2005-11-16
Further Info :

Pubmed ID

7903515

DOI: Digital Object Identifier

7903515

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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