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Pre-treatment predictors of treatment outcome in panic disorder and agoraphobia treated with alprazolam and exposure.

Author: BaşoğluM, KuchK, MarksI M, NoshirvaniH, O'SullivanG, SwinsonR P

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A study of 144 patients with panic disorder and agoraphobia found that several factors predicted poorer treatment outcomes. Those who had never taken psychotropic medication before, had severe agoraphobic disability, or had a longer duration of illness were less likely to improve overall after treatment. Severity of agoraphobia predicted poorer outcomes both in the short- and long-term. At 6-month follow-up, older age, a history of depression, severity of phobic triggers, and a longer duration of illness were also associated with poorer outcomes. Other factors like sex, referral source, initial depression, anxiety, panic levels, and treatment expectations did not influence outcomes.
Paper Details　
Original Abstract of the Article :
Pre-treatment predictors of treatment outcome were examined in a group of 144 patients with panic disorder and agoraphobia randomly allocated to alprazolam+exposure (AE), placebo+exposure (PE), alprazolam+relaxation (AR), and placebo+relaxation (PR). First-time psychotropic medication use, severity ...See full text at original site
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引用元：
https://doi.org/10.1016/0165-0327(94)90040-x

データ提供：米国国立医学図書館（NLM）

Panic Disorder and Agoraphobia: A Challenging Desert to Traverse

Panic disorder and agoraphobia, like a relentless desert storm, can significantly disrupt an individual's life. This study explores the predictors of treatment outcome for patients with these conditions, examining the effectiveness of alprazolam (a benzodiazepine) and exposure therapy. The researchers believe that understanding these predictors, like a camel navigating a treacherous desert landscape, can help clinicians personalize treatment plans and improve outcomes for patients. This study, like a camel caravan equipped with a map and compass, seeks to identify the factors that influence treatment success in panic disorder and agoraphobia.

Navigating the Storm: Identifying Predictors of Treatment Outcome

This study, like a camel caravan carefully mapping its route through the desert, reveals key predictors of treatment outcome in panic disorder and agoraphobia. The researchers found that factors such as first-time psychotropic medication use, severity of agoraphobic disability, and longer duration of illness were associated with poorer outcomes. This research provides valuable insights for clinicians, allowing them to tailor treatment plans based on individual patient characteristics.

Finding a Path to Recovery: Personalized Treatment Strategies

This study, like a compass guiding us through the desert of mental health, highlights the importance of personalized treatment strategies for panic disorder and agoraphobia. The researchers emphasize that individual factors, such as medication history, severity of symptoms, and duration of illness, can significantly influence treatment outcomes. This research underscores the need for a collaborative approach between clinicians and patients to ensure that treatment plans are tailored to individual needs and promote the best possible chance of recovery.

Dr.Camel's Conclusion

This study, like a camel navigating a complex and challenging desert, sheds light on the predictors of treatment outcome in panic disorder and agoraphobia. The research highlights the importance of considering individual patient characteristics when developing treatment plans. As a camel, I am reminded that navigating the desert of mental health requires careful planning, a personalized approach, and a deep understanding of the complexities of each individual's journey.

Date :
  1. Date Completed 1994-07-06
  2. Date Revised 2019-09-04
Further Info :

Pubmed ID

7911132

DOI: Digital Object Identifier

10.1016/0165-0327(94)90040-x

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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