Placebo-controlled trial of vaccination with recombinant glycoprotein D of herpes simplex virus type 2 for immunotherapy of genital herpes.

Author: AdairS F, BarnumG, BurkeR L, CoreyL, KostR G, KrauseP R, MeierJ L, SavareseB, SekulovichR, StrausS E

Paper Details 
Original Abstract of the Article :
Immunotherapy of chronic viral diseases with vaccines is an important but unproven concept. We investigated the effect of a vaccine containing recombinant glycoprotein D (gD2) of herpes simplex virus type 2 (HSV-2) on the frequency of symptomatic outbreaks in patients with genital herpes. 98 patient...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1016/s0140-6736(94)92581-x

データ提供:米国国立医学図書館(NLM)

Hope on the Horizon: A Vaccine for Genital Herpes

Genital herpes, a persistent and recurring viral infection, has long been a challenge for patients and medical professionals. This [placebo-controlled trial] investigates the potential of a [vaccine containing recombinant glycoprotein D (gD2) of herpes simplex virus type 2 (HSV-2)] as a novel immunotherapy for this condition. The authors explore the vaccine's efficacy in reducing the frequency of [symptomatic outbreaks] and its impact on HSV-2-specific antibody responses. This research provides a glimmer of hope for the development of effective treatments for this challenging viral infection.

A Promising Step Toward Controlling Genital Herpes

This study offers a ray of hope for individuals struggling with [genital herpes]. The results of this [placebo-controlled trial] suggest that the [gD2 vaccine] may be a promising approach to reducing the frequency of [symptomatic outbreaks] and boosting the body's immune response against HSV-2. While further research is needed to confirm these findings, this study represents a significant step forward in the search for effective treatments for this persistent and recurring viral infection.

A New Dawn for Herpes Management: Staying Informed and Hopeful

The results of this [placebo-controlled trial] offer a glimmer of hope for individuals with [genital herpes]. While the gD2 vaccine demonstrated promising results in reducing the frequency of symptomatic outbreaks, it's important to note that further research is needed to confirm these findings. In the meantime, staying informed about the latest advancements in herpes management and maintaining open communication with healthcare professionals is crucial. With continued research and innovation, there is a growing optimism for the development of more effective treatments for this challenging viral infection.

Dr.Camel's Conclusion

This research represents a promising step towards conquering the challenges of genital herpes. Like a desert traveler seeking an oasis, researchers are tirelessly exploring new avenues for controlling this persistent and recurring viral infection. The gD2 vaccine shows promise in reducing the frequency of outbreaks and boosting the body's immune response. While further research is crucial, this study offers a ray of hope for individuals seeking effective treatments for genital herpes. With continued dedication to scientific exploration, we can navigate the complexities of this viral infection and strive to provide relief and improved quality of life for those affected.

Date :
  1. Date Completed 1994-07-05
  2. Date Revised 2019-06-11
Further Info :

Pubmed ID

7911177

DOI: Digital Object Identifier

10.1016/s0140-6736(94)92581-x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.