Influence of cannabidiol on secobarbital effects and plasma kinetics.

Author: DaltonW S, ForneyR B, LembergerL, MartzR, RoddaB E

Paper Details 
Original Abstract of the Article :
To investigate the possible metabolic interaction between cannabidiol (CBD) and secobarbital, 6 male volunteers received 150 mg/70 kg sodium secobarbital orally immediately after smoking a marihuana cigarette prepared to deliver 0, 150, or 500 mug/kg CBD. The study was performed in a double-blind ma...See full text at original site
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引用元:
https://doi.org/10.1002/cpt1976206695

データ提供:米国国立医学図書館(NLM)

Cannabidiol and Secobarbital: Navigating the Desert of Drug Interactions

The interactions between different drugs can be complex and unpredictable, often leading to unexpected effects. This study investigates the potential metabolic interaction between cannabidiol (CBD), a compound found in cannabis, and secobarbital, a barbiturate used as a sedative. The study aimed to determine whether CBD affects the metabolism and effects of secobarbital.

A Desert Oasis: No Significant Interaction

The study found that CBD, at the doses administered, did not significantly alter the metabolism or clinical effects of secobarbital. This suggests that CBD does not inhibit the breakdown of secobarbital in the body. It’s like finding a calm oasis in the middle of a turbulent desert, where two substances coexist without causing major disruptions.

Navigating the Desert: A Cautious Approach to Drug Combinations

This research highlights the importance of carefully considering potential drug interactions. While this study suggests that CBD and secobarbital do not interact significantly, it's essential to consult with a healthcare professional before combining any medications, even those considered natural or herbal. It’s like navigating a desert with a trusted guide, ensuring that you are informed and prepared for any potential challenges.

Dr. Camel's Conclusion

This study provides valuable information about the potential interaction between CBD and secobarbital. However, it’s important to note that this was a small study with limited participants, and further research is needed to confirm these findings. It’s a reminder that the desert of drug interactions is vast and complex, and we must always approach drug combinations with caution.

Date :
  1. Date Completed 1977-01-28
  2. Date Revised 2019-05-09
Further Info :

Pubmed ID

791563

DOI: Digital Object Identifier

10.1002/cpt1976206695

Related Literature

SNS
PICO Info
in preparation
Languages

English

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