Effective short-course treatment of acute group A beta-hemolytic streptococcal tonsillopharyngitis. Ten days of penicillin V vs 5 days or 10 days of cefpodoxime therapy in children.

Author: AronoffS C, BlumerJ L, GoochW M, JacobsR F, MusserJ M, PichicheroM E, RodriguezW

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To compare bacteriologic and clinical efficacy and safety of 10 vs 5 days of cefpodoxime proxetil vs 10 days of penicillin V potassium for the treatment of acute group A beta-hemolytic streptococcal tonsillopharyngitis in children. DESIGN: Prospective, randomized, observer-blind, multice...See full text at original site
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引用元:
https://doi.org/10.1001/archpedi.1994.02170100051010

データ提供:米国国立医学図書館(NLM)

Evaluating the Effectiveness of Short-Course Antibiotics for Streptococcal Pharyngitis

Streptococcal pharyngitis, commonly known as strep throat, is a bacterial infection that causes inflammation of the throat and tonsils. Antibiotics are typically prescribed to treat this infection, but the optimal duration of treatment is still under debate.

This study compared the effectiveness of two different antibiotic regimens for treating strep throat in children. One regimen involved 10 days of penicillin V, while the other involved 5 days of cefpodoxime. The researchers assessed the effectiveness of each regimen by measuring the rate of bacterial eradication and clinical improvement. The study also evaluated the safety of each treatment regimen.

The study found that both 5-day and 10-day cefpodoxime regimens were more effective in eradicating bacteria than the 10-day penicillin V regimen. The study also found that both cefpodoxime regimens were well-tolerated, with few side effects. These findings suggest that a 5-day course of cefpodoxime may be an effective and safe alternative to a 10-day course of penicillin V for treating strep throat in children.

The Importance of Short-Course Antibiotics

This study highlights the importance of using the shortest possible course of antibiotics to treat bacterial infections. Short-course antibiotic regimens can reduce the risk of antibiotic resistance and minimize potential side effects. Clinicians can use this research to inform their decisions about antibiotic therapy for strep throat in children.

Understanding Antibiotic Resistance

Antibiotic resistance is a growing global health concern. The overuse and misuse of antibiotics can lead to the development of bacteria that are resistant to these drugs. This research underscores the need for responsible antibiotic use, including using the shortest possible course of treatment to prevent antibiotic resistance.

Dr.Camel's Conclusion

This research is like a compass guiding us through the desert of antibiotic therapy. By understanding the effectiveness of different antibiotic regimens, we can make informed decisions about treatment and help prevent the development of antibiotic resistance. It's a reminder that we must use antibiotics wisely, just as a traveler in the desert would conserve their precious water supply.

Date :
  1. Date Completed 1994-10-26
  2. Date Revised 2023-12-13
Further Info :

Pubmed ID

7921095

DOI: Digital Object Identifier

10.1001/archpedi.1994.02170100051010

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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