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Comparison of the efficacy and tolerability of moclobemide and maprotiline in depressed patients treated by general practitioners.
Author: DickP, GachoudJ P, KöhlerM
Original Abstract of the Article :
We report the results of a multicenter, double-blind study conducted in a general practice setting, in which the efficacy and tolerability of moclobemide, a new antidepressant drug of the reversible inhibitor of monoamine oxidase type A class, were compared with those of maprotiline, a noradrenaline...See full text at original site
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引用元:
https://doi.org/10.1097/00002826-199417001-00005
データ提供:米国国立医学図書館(NLM)
Moclobemide vs. Maprotiline: Navigating the Desert of Depression
The desert of [depression] can be a lonely and isolating place, with feelings of hopelessness and despair casting a long shadow over the lives of those affected. This study, like a compassionate traveler offering solace in the midst of hardship, compares the efficacy and tolerability of two antidepressant medications: [moclobemide] and [maprotiline]. Researchers conducted a double-blind, multicenter study involving 130 outpatients with major depression, assessing the effects of both medications over a four-week period. The study found that moclobemide was as effective as maprotiline in reducing depressive symptoms, but was associated with fewer side effects, particularly somnolence and dry mouth.
Moclobemide: A Potentially Better Choice for Depression
This study suggests that moclobemide may be a better choice for patients with depression who are concerned about side effects. While both medications demonstrated efficacy, moclobemide's favorable tolerability profile could make it a more appealing option for some individuals. However, it's important to remember that this study focused on a specific population and dosage, and individual responses to medications can vary widely.
Navigating the Desert of Depression: Seeking Professional Guidance
Depression is a serious condition that requires professional care. It's crucial to consult with your healthcare provider to discuss your symptoms, explore potential treatment options, and find the best course of action for your individual needs. Remember, seeking help and working with a qualified mental health professional is a vital step towards navigating the desert of depression and finding your path to recovery.
Dr.Camel's Conclusion
This study highlights the importance of finding the right medication for depression, considering both efficacy and tolerability. It underscores the need for personalized treatment approaches, taking into account individual patient needs and preferences. It's a reminder that the journey through the desert of depression is best undertaken with the support of healthcare professionals and a commitment to finding the right path to recovery.
Date :
- Date Completed 1994-12-21
- Date Revised 2019-09-14
Further Info :
Related Literature
English
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