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Three-year follow-up of the Oxford Cholesterol Study: assessment of the efficacy and safety of simvastatin in preparation for a large mortality study.
Author: ArmitageJ, CollinsR, FatemianM, KearneyE, KeechA, LawsonA, LyonV, MacMahonS, MindellJ, WallendszusK
Original Abstract of the Article :
We report the results of a randomized single-centre study designed to assess the effects of simvastatin on blood lipids, blood biochemistry, haematology and other measures of safety and tolerability in preparation for a large-scale multicentre mortality study. Six hundred and twenty-one individuals ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1093/oxfordjournals.eurheartj.a060485
データ提供:米国国立医学図書館(NLM)
Simvastatin: A Beacon of Hope in the Desert of Heart Disease
Heart disease is a major health concern, like a looming sandstorm threatening to engulf us. This study examines the effects of simvastatin, a cholesterol-lowering drug, on individuals at increased risk for coronary heart disease. The researchers aim to assess the safety and efficacy of simvastatin in preparation for a larger-scale mortality study, hoping to find a way to protect against the devastating effects of heart disease.
Simvastatin: A Shield Against the Heart Disease Storm
The study found that simvastatin effectively reduced cholesterol levels, particularly LDL cholesterol, which is considered the 'bad' cholesterol. It also produced a small increase in HDL cholesterol, the 'good' cholesterol. These findings suggest that simvastatin may play a significant role in protecting against heart disease.
Maintaining a Healthy Heart in the Desert
This study reinforces the importance of maintaining healthy cholesterol levels for optimal heart health. By understanding the role of cholesterol and the benefits of cholesterol-lowering medications, we can take proactive steps to protect our cardiovascular health and navigate the journey of life with greater confidence. Just like a camel needs to stay hydrated in the desert, we need to be mindful of our cholesterol levels to maintain a healthy heart.
Dr.Camel's Conclusion
This study provides valuable data on the efficacy and safety of simvastatin in managing cholesterol levels and reducing the risk of heart disease. It's a testament to the ongoing efforts of researchers who are constantly searching for new and effective ways to combat this silent threat. By understanding the intricacies of heart health and embracing preventive measures, we can effectively weather the storms that threaten our cardiovascular well-being.
Date :
- Date Completed 1994-07-18
- Date Revised 2022-03-30
Further Info :
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