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Unsuspected bronchospasm in association with topical timolol--a common problem in elderly people: can we easily identify those affected and do cardioselective agents lead to improvement?

Author: ChauG, DiggoryP, HeyworthP, McKenzieS, SharmaA

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated respiratory function in elderly glaucomatous patients receiving topical timolol therapy. Changing from timolol to pilocarpine or betaxolol improved lung function, and specific symptoms were identified to predict patients likely to benefit from therapy change.
Paper Details　
Original Abstract of the Article :
The extent of impairment of respiratory function in a group of 52 elderly, glaucomatous patients receiving topical timolol therapy was investigated. To predict those patients who were likely to benefit from changing therapy, symptoms were elicited by direct questioning, and lung spirometry was measu...See full text at original site
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引用元：
https://doi.org/10.1093/ageing/23.1.17

データ提供：米国国立医学図書館（NLM）

The Unexpected Side Effects of Eye Drops

This study explores the intriguing world of ophthalmology, focusing on the potential respiratory complications associated with topical timolol, a common eye drop medication. The researchers investigated the effects of timolol on a group of elderly patients with glaucoma, a condition that affects eye pressure. They found that timolol, while effective in controlling glaucoma, can lead to unsuspected bronchospasm in some patients, particularly the elderly. This is like a camel's gentle breeze that can turn into a sandstorm for some individuals. The researchers also found that switching to other medications, such as pilocarpine or betaxolol, could improve lung function.

Identifying and Managing Bronchospasm

The study identified a specific set of symptoms that could be used to predict those patients who are likely to experience bronchospasm. These include exertional dyspnoea (shortness of breath during exercise), cough with sputum, and a high dyspnoea score. These findings are like a compass in the desert, helping clinicians to identify and manage this potentially serious side effect.

Navigating the Desert of Respiratory Health

This study serves as a reminder that even seemingly simple medications can have unexpected side effects. It's essential for patients to be aware of these potential risks and to work closely with their healthcare providers to manage any complications. It's always a good idea to stay hydrated and stay informed when navigating the vast desert of respiratory health.

Dr.Camel's Conclusion

This study is a reminder that even the most common medications can have unexpected side effects. It's always a good idea to be aware of these potential risks and to talk to your doctor if you experience any unusual symptoms. Knowledge is the key to navigating the vast desert of health and well-being.

Date :
  1. Date Completed 1994-07-18
  2. Date Revised 2019-05-12
Further Info :

Pubmed ID

8010165

DOI: Digital Object Identifier

10.1093/ageing/23.1.17

Related Literature

Article Analysis
・Side Effects of betaxolol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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