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The use of confidence intervals to describe the precision of trough/peak ratios for diltiazem CD in the treatment of hypertension.

Author: MeevesS G, ParkG D

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study evaluated the safety, efficacy, and trough/peak antihypertensive effects of once-daily diltiazem CD 300 mg in patients with essential hypertension. Diltiazem CD effectively lowered blood pressure and was well tolerated.
Paper Details　
Original Abstract of the Article :
Once-daily diltiazem hydrochloride, CARDIZEM CD (diltiazem CD) 300 mg, was evaluated for safety, efficacy, and the relationship between peak and trough antihypertensive effects in a multicenter, placebo-controlled, parallel design trial. After a 4- to 6-week placebo baseline period, 111 patients wit...See full text at original site
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引用元：
https://doi.org/10.1002/j.1552-4604.1994.tb03991.x

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 1994-08-04
  2. Date Revised 2019-08-25
Further Info :

Pubmed ID

8021331

DOI: Digital Object Identifier

10.1002/j.1552-4604.1994.tb03991.x

Related Literature

Article Analysis
・Effects of diltiazem
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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