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Comparative effects of H2-receptor antagonists on subjective and objective assessments of sleep.

Author: DukeJ C, ImesN K, MellowM H, OrrW C

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Cimetidine, famotidine, and ranitidine, three H2-receptor antagonists, showed different effects on nocturnal and daytime sleepiness.
Paper Details　
Original Abstract of the Article :
Clinically, it is common for patients to experience drowsiness in association with consumption of H1-receptor antagonists. Reported side-effects with H2-receptor antagonists include insomnia and somnolence. The present study was designed to assess and compare the effects of three H2-receptor antagon...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.1111/j.1365-2036.1994.tb00279.x

データ提供：米国国立医学図書館（NLM）

The Sleep-Inducing Effects of H2-Receptor Antagonists: A Comparative Study

My scientific curiosity always leads me to explore the fascinating world of [pharmacology] and [sleep medicine]. This study delves into the effects of [H2-receptor antagonists], a class of drugs commonly used to treat heartburn and stomach ulcers, on sleep quality. Researchers conducted a rigorous [double-blind, randomized study] to compare the impact of [cimetidine, famotidine, and ranitidine] on both nocturnal and daytime sleepiness.

A Quest for Optimal Sleep

The study found that [the effects of H2-receptor antagonists on sleep varied], suggesting that certain drugs may be better suited for individuals with specific sleep needs. This research highlights the importance of [individualized therapy] in managing sleep disorders.

Finding Balance in the Sand of Sleep

Imagine a caravan crossing the vast desert. Some camels are naturally more prone to drowsiness, while others are easily awakened. This research is like finding the perfect balance of sand in the hourglass of sleep. By understanding the specific effects of each H2-receptor antagonist, we can find the optimal medication to help each camel, or patient, find the restful slumber they need.

Dr.Camel's Conclusion

This research provides valuable insights into the complex relationship between medications and sleep. By comparing the effects of different H2-receptor antagonists on sleep patterns, the study underscores the importance of individualized therapy, ensuring that each patient receives the most appropriate treatment to achieve optimal sleep quality.

Date :
  1. Date Completed 1994-08-25
  2. Date Revised 2019-08-30
Further Info :

Pubmed ID

8038352

DOI: Digital Object Identifier

10.1111/j.1365-2036.1994.tb00279.x

Related Literature

Article Analysis
・Side Effects of cimetidine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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