Ocufen (flurbiprofen) in the treatment of ocular pain after radial keratotomy.

Author: CheethamJ K, DeGryseR, GwonA, VaughanE R

Paper Details 
Original Abstract of the Article :
Ocular pain is often treated with systemic analgesics, which are associated with some undesirable side effects. Because nonsteroidal anti-inflammatory drugs are thought to be peripheral analgesics, we decided to evaluate the local analgesic effect of flurbiprofen. After an initial study in 29 patien...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/8044980

データ提供:米国国立医学図書館(NLM)

Ocufen (flurbiprofen): A Targeted Approach to Ocular Pain

In the world of [ophthalmology], managing [ocular pain] is a frequent challenge. While [systemic analgesics] are often employed, they can come with undesirable side effects. This study investigates the local analgesic efficacy of [flurbiprofen], a nonsteroidal anti-inflammatory drug, in relieving ocular pain after [radial keratotomy]. The researchers conducted a meticulously controlled, double-masked, parallel-group clinical trial, comparing the effects of topically applied [0.03% flurbiprofen sodium ophthalmic solution] with a vehicle control.

Targeted Relief: Flurbiprofen's Promise for Ocular Pain

The study's findings demonstrate that flurbiprofen effectively reduces ocular pain after radial keratotomy, with clinically significant pain relief observed at various time points. The researchers also found that flurbiprofen does not affect [corneal sensitivity], suggesting a targeted approach that minimizes potential side effects.

A New Perspective on Pain Management: Balancing Efficacy and Safety

This study highlights the potential benefits of topical flurbiprofen for managing ocular pain after surgery. Its targeted action, coupled with a favorable safety profile, offers a promising alternative to systemic analgesics. The research underscores the importance of considering localized treatment options whenever possible, minimizing systemic exposure and potential side effects.

Dr.Camel's Conclusion

Just as a camel's keen eyesight helps it navigate the desert landscape, flurbiprofen provides a targeted approach to managing ocular pain. This research offers a valuable oasis of knowledge, demonstrating the efficacy and safety of this localized treatment option, paving the way for more effective and patient-centered care.

Date :
  1. Date Completed 1994-08-30
  2. Date Revised 2017-01-24
Further Info :

Pubmed ID

8044980

DOI: Digital Object Identifier

8044980

SNS
PICO Info
in preparation
Languages

English

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