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[The effect of an antihypertensive drug during psychological stress. A double-blind study].

Author: DahmeB, EulenbergerD, RöslerF, WegenerH

English AbstractA summary of a research paper/publication written in English for a wider audience.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Briserin, a combination drug containing reserpine, clopamide, and dihydroergocristin, effectively reduced blood pressure in hypertensive patients compared to placebo. The medication lowered blood pressure under stress and at rest, with more significant effects in situations with low or medium stress. However, Briserin may impair reaction time, perceptual speed, and short-term memory.
Paper Details　
Original Abstract of the Article :
A sample of 20 patients suffering hypertension (with a moderate rise in blood pressure) was randomly divided into two treatment groups of equal size. The patients of one group received antihypertension treatment with the combination drug Briserin¿ (containing 0.1 mg reserpine, 5 mg clopamide, 0.5 mg...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/809046

データ提供：米国国立医学図書館（NLM）

Managing Hypertension Under Stress

Hypertension, a condition characterized by high blood pressure, is like a desert windstorm that can put extra strain on the heart and blood vessels. This double-blind study investigates the effect of an antihypertensive drug on blood pressure during psychological stress.

The Impact of Stress on Blood Pressure

The study found that the antihypertensive drug Briserin significantly reduced both systolic and diastolic blood pressure in patients with moderate hypertension, even during stressful situations. However, the effect was less pronounced in situations with heavy emotional or cognitive load.

Stress Management: A Key to Heart Health

The study highlights the importance of managing stress for individuals with hypertension. While antihypertensive drugs can play a crucial role in controlling blood pressure, lifestyle changes and stress management techniques are also essential for long-term heart health.

Dr.Camel's Conclusion

The study offers valuable insights into the interplay between stress and hypertension. It emphasizes the importance of a holistic approach to managing hypertension, combining medication with stress management strategies to protect the heart and maintain overall well-being. It’s like finding a cool oasis in the middle of a scorching desert – a place where you can find relief from the pressures of life.

Date :
  1. Date Completed 1975-11-25
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

809046

DOI: Digital Object Identifier

809046

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Languages

German

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