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A double-blind, placebo-controlled trial by the sublingual route of immunotherapy with a standardized grass pollen extract.

Author: AndréC, HassounS, Le SellinJ, SabbahA, SicardH

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study found that sublingual immunotherapy with a solution of purified, standardized grass pollen extract was effective in reducing symptoms of seasonal rhinoconjunctivitis in grass-pollen-sensitive patients.
Paper Details　
Original Abstract of the Article :
Fifty-eight patients with well-documented history of seasonal rhinoconjunctivitis caused by grass pollens were allocated randomly on a double-blind basis to receive either sublingual therapy with a solution of purified, standardized allergen preparation (Stallergènes) or a matched placebo for 17 wee...See full text at original site
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引用元：
https://doi.org/10.1111/j.1398-9995.1994.tb02273.x

データ提供：米国国立医学図書館（NLM）

Sublingual Immunotherapy for Grass Pollen Allergy: A Promising Approach

Navigating the world of allergies can be like wandering through a desert of sniffles and sneezes. This study explores the use of sublingual immunotherapy (SLIT) with a standardized grass pollen extract as a potential treatment for seasonal rhinoconjunctivitis, a common allergy characterized by nasal and eye symptoms. The researchers conducted a double-blind, placebo-controlled trial to evaluate the effectiveness of SLIT in reducing allergy symptoms and medication usage.

Sublingual Immunotherapy's Positive Impact on Allergy Symptoms

The study found that patients receiving SLIT experienced significantly fewer symptoms of rhinitis and conjunctivitis during the pollen season compared to those receiving placebo. They also used significantly less medication for symptom relief. This suggests that SLIT may be an effective and safe treatment for grass pollen allergy.

Benefits of Sublingual Immunotherapy for Allergy Sufferers

This study highlights the potential benefits of SLIT in managing grass pollen allergy. It offers a promising approach for individuals who are seeking alternatives to traditional allergy treatments. SLIT is a convenient and well-tolerated treatment option that could help allergy sufferers navigate the desert of pollen season with greater ease.

Dr. Camel's Conclusion

This study reveals the potential of SLIT in mitigating allergy symptoms and improving quality of life for patients with grass pollen allergy. It is a reminder that the desert of allergy research is constantly evolving, and new therapies are emerging that can help us combat these challenging conditions.

Date :
  1. Date Completed 1994-10-14
  2. Date Revised 2019-08-21
Further Info :

Pubmed ID

8092425

DOI: Digital Object Identifier

10.1111/j.1398-9995.1994.tb02273.x

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