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Hydrochlorothiazide treatment of children with hypercalciuria: effects and side effects.
Author: DobosM, MiltényiM, ReuszG S, TulassayT
Original Abstract of the Article :
Urinary excretion of calcium and the changes in serum cholesterol fractions were investigated in 15 children with renal hypercalciuria, following 3-month hydrochlorothiazide (HCT) treatment (daily dose 1 mg/kg). Urinary calcium excretion (expressed as the ratio of calcium to creatinine) reached its ...See full text at original site
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引用元：
https://doi.org/10.1007/BF01213325
データ提供：米国国立医学図書館（NLM）
Hydrochlorothiazide for Hypercalciuria in Children: A Balancing Act in Pediatric Treatment
Hypercalciuria, a condition characterized by high levels of calcium in the urine, can have significant implications for pediatric health. This study examines the effectiveness and safety of hydrochlorothiazide (HCT), a diuretic medication, in treating hypercalciuria in children. The researchers investigated the effects of HCT on urinary calcium excretion and serum cholesterol levels in 15 children with renal hypercalciuria.
A Balancing Act: Managing Hypercalciuria and Cholesterol Levels
The study found that HCT effectively reduced urinary calcium excretion in children with hypercalciuria. However, the researchers also noted a significant increase in total serum cholesterol and LDL cholesterol levels, suggesting a potential trade-off between reducing calcium levels and increasing cholesterol levels. This highlights the need for careful monitoring of cholesterol levels in children treated with HCT.
Navigating the Desert of Pediatric Treatment: Weighing the Risks and Benefits
This study underscores the importance of carefully weighing the risks and benefits of HCT treatment for hypercalciuria in children. While HCT can effectively reduce urinary calcium levels, it can also have potential adverse effects on cholesterol levels. This highlights the need for individualized treatment plans and close monitoring to optimize outcomes and minimize risks for pediatric patients.
Dr.Camel's Conclusion
This study investigates the effectiveness and safety of hydrochlorothiazide (HCT) in treating hypercalciuria in children. While HCT effectively reduces urinary calcium levels, it can also lead to increased cholesterol levels. This highlights the need for careful monitoring and individualized treatment plans to balance the benefits and risks of HCT therapy for pediatric patients. Just as a camel navigates the vast and unforgiving desert, healthcare providers must carefully consider all aspects of treatment to ensure the best possible outcomes for their patients.
Date :
- Date Completed 1994-04-21
- Date Revised 2019-09-04
Further Info :
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